@misc{oai:repo.qst.go.jp:00068597,
 author = {Wang, Xufei and Konishi, Teruaki and Hamano, Tsuyoshi and Yasuda, Nakahiro and Imaseki, Hitoshi and Ishikawa, Takahiro and Iso, Hiroyuki and Suya, Noriyoshi and Yukawa, Masae and 王 旭飛 and 小西 輝昭 and 濱野 毅 and 安田 仲宏 and 今関 等 and 石川 剛弘 and 酢屋 徳啓 and 湯川 雅枝},
 month = {Jul},
 note = {The Single Particle Irradiation to Cells (SPICE) facility has been constructed for biological cell irradiation, with the ability to deliver exactly defined numbers of ions into a small region within the area of an individual living cell. The SPICE is able to provide 3.4 MeV proton and 5.1 MeV alpha particle microbeams using a mono-bloc triplet quadrupole lens (Q lens), which is located just before the beam exit. We are currently adopting a scintillation counter that detects ions after passing through a biological cell, and a pair of electrostatic beam deflecting plates to realize single-ion irradiation. The output signal of the counter is fed to a computer-based scaler, and then a high voltage is applied for the deflecting plates to deflect the beam, once a defined number of protons has detected. The dosage precision of the single particle irradiation system has been tested for 3.4 MeV protons using 90 um thick CR-39 detector. The statistics of the etched pits number on the CR-39 has demonstrated that the single-ion irradiation system is capable of quantitative irradiation with the efficiency (the probability of which the number of traversal ion is equal to the preset value) measured to be 95.1%, ICNMTA2006},
 title = {Development of single particle microbeam irradiation system for radiation biology},
 year = {2006}
}