{"created":"2023-05-15T14:49:52.792163+00:00","id":68287,"links":{},"metadata":{"_buckets":{"deposit":"2af4c49c-3c50-4941-b488-5d854d9c62e9"},"_deposit":{"created_by":1,"id":"68287","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"68287"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00068287","sets":["10:28"]},"author_link":["670420","670417","670418","670415","670416","670421","670419"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2005-12-10","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"放射線の生物に対する影響については、これまで様々な研究がなされてきた \nが、真核生物への放射線の影響やその耐性機構は複雑で、いまだに不明瞭な点 \nが多い。今回我々は、出芽酵母における放射線影響のメカニズムの解析を行な \nうため、必須遺伝子を除く全遺伝子が各々破壊された変異株の集合体、Yeast \nDeletion Poolを用いて、ガンマ線に感受性もしくは耐性となる破壊株を \nbarcode arrayにより網羅的な解析を行なった。その結果、ガンマ線に感受性 \nになる株として得られた遺伝子を機能別のカテゴリーに分けると、Cell \ncycle やDNA修復を含むカテゴリーに最も多く(約30%)含まれた。更に、機能未 \n知の感受性候補株について単独株での解析を行ったが、既知のRAD 変異株のよ \nうに、放射線に超感受性を示す様な新たな株は見いだせなかった。また、耐性 \n株のスクリーニングでは、幾つかの候補株が得られ、現在解析中である。","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"日本分子生物学会第２８回大会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"矢澤, 彌"}],"nameIdentifiers":[{"nameIdentifier":"670415","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"岩崎, 均"}],"nameIdentifiers":[{"nameIdentifier":"670416","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"中島, 徹夫"}],"nameIdentifiers":[{"nameIdentifier":"670417","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"木村, 真三"}],"nameIdentifiers":[{"nameIdentifier":"670418","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"植村, 浩"}],"nameIdentifiers":[{"nameIdentifier":"670419","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"中島 徹夫","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"670420","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"木村 真三","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"670421","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"電離放射線に感受性または耐性となる出芽酵母の遺伝子破壊株の単離と解析　","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"電離放射線に感受性または耐性となる出芽酵母の遺伝子破壊株の単離と解析　"}]},"item_type_id":"10005","owner":"1","path":["28"],"pubdate":{"attribute_name":"公開日","attribute_value":"2005-12-12"},"publish_date":"2005-12-12","publish_status":"0","recid":"68287","relation_version_is_last":true,"title":["電離放射線に感受性または耐性となる出芽酵母の遺伝子破壊株の単離と解析　"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T20:27:54.675982+00:00"}