{"created":"2023-05-15T14:49:48.354017+00:00","id":68187,"links":{},"metadata":{"_buckets":{"deposit":"d22b64e7-0777-4fdc-9dbe-005885bc0a5f"},"_deposit":{"created_by":1,"id":"68187","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"68187"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00068187","sets":["10:28"]},"author_link":["669465","669462","669461","669464","669466","669463","669467"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2005-10-08","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"無血清初代培養系でのスレーティーマウスの表皮メラノサイトの増殖と分化の特徴を調べたところ、増殖能は野生型と同等であったが、分化能が低かった。メラノサイトの分化に重要なチロシナーゼの活性やチロシナーゼ関連タンパク質２の発現が弱く、黄色メラニンの量は変わらなかったものの、黒色メラニンの量が少なかった。スレーティー遺伝子はチロシナーゼの活性やチロシナーゼ関連タンパク質２の発現を制御し、黒色メラニンの産生を制御する働きがあると示唆される。","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"第７６回日本動物学会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"廣部, 知久"}],"nameIdentifiers":[{"nameIdentifier":"669461","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"若松, 一雅"}],"nameIdentifiers":[{"nameIdentifier":"669462","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"伊藤, 祥輔"}],"nameIdentifiers":[{"nameIdentifier":"669463","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"河, 陽子"}],"nameIdentifiers":[{"nameIdentifier":"669464","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"相馬, 良直"}],"nameIdentifiers":[{"nameIdentifier":"669465","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"溝口, 昌子"}],"nameIdentifiers":[{"nameIdentifier":"669466","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"廣部 知久","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"669467","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"マウス表皮メラノサイトの増殖・分化におけるスレーティー遺伝子の役割","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"マウス表皮メラノサイトの増殖・分化におけるスレーティー遺伝子の役割"}]},"item_type_id":"10005","owner":"1","path":["28"],"pubdate":{"attribute_name":"公開日","attribute_value":"2005-10-12"},"publish_date":"2005-10-12","publish_status":"0","recid":"68187","relation_version_is_last":true,"title":["マウス表皮メラノサイトの増殖・分化におけるスレーティー遺伝子の役割"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T20:29:04.612277+00:00"}