@misc{oai:repo.qst.go.jp:00067956,
 author = {Yoshikawa, Kyosan and Sagou, Kenji and Tamura, Katsumi and Ishikawa, Hiroyuki and Koga and Kandatsu, Susumu and Tsujii, Hirohiko and Tanada, Shuji and et.al and 吉川 京燦 and 佐合 賢治 and 田村 克巳 and 石川 博之 and 古賀 雅久 and 神立 進 and 辻井 博彦 and 棚田 修二},
 month = {Jun},
 note = {Objectives:The combination of PET and CT,the combined PET/CT,could provide more accurate information than either modality alone in the initial diagnosis and for therapy management. In lung and upper abdominal region,however,there is potential mis-registration from differences in the breathing pattern between PET and CT date sets. One of solutions for this kind of artifact might be gated CT and gated PET imaging,but some breathing protocols for CT scans could reduce this kind of artifact using dual-modality PET/CT. We performed a breath holding method for reduction of mis-registration artifact of chest PET/CT fusion image and evaluated the usefulness of the method.
Methods:We studied 39 cases(45 studies) using PET/CT, Siemens Biograph. There were cases of 32 non-small cell lung cancers (38 studies),5 metastatic lung cancers,one lung tuberculosis,and one pulmonary embolism.37 chest PET/CT studies were performed using C-11 methionine and 8 were done using FDG.Each CT scan for thorax region was performed with holding breath at the end of expiration phase,and PET measurements were done with natural breathing in resting state.Diaphragm,chest wall, mediastinum and tumor lesion were evaluated visually in coronal PET/CT fusion images, and were evaluated according to the three-grade system,such as fail,almost and good.
Results:Mis-registration artifact of chest PET/CT fusion image caused by our holding breath method was not frequent in whole our cases.Fail,almost and good fitting results at diaphragm were 8.9%,20.0% and 71.1%,at chest wall were 0%,2.2% and 97.8%,at mediastinum were 0%,2.2% and 97.8%,and at tumor lesion were 3.2%,3.2% and 93.6%,respectively.Fitting errors,in case those exist,tended to exist at posterior portion of diaphragm,and diaphragm also tended to be lower portion in CT than in PET.There was less fitting error in upper and middle lung field.
Conclusions:A simple method,holding breath at the end of expiration phase,for CT imaging might be useful for reduction of mis-registration artifact of chest PET/CT fusion image caused by breathing movement of thorax., Society of nuclear medicine's 51st. annual meeting},
 title = {A METHOD FOR REDUCTION OF MIS-REGISTRATION ARTIFACT OF CHEST PET/CT FUSION IMAGE CAUSED BY BREATHING MOVEMENT OF THORAX.},
 year = {2004}
}