@misc{oai:repo.qst.go.jp:00067930,
 author = {Ishikawa, Yuuji and 石川 裕二},
 month = {Nov},
 note = {In order to know the general pattern of axonogenesis in vertebrates, we have examined axonogenesis in the embryonic brain of a teleost fish, medaka (Oryzias latipes), and the results were compared with previous studies in zebrafish and mouse. The axons and somata were stained immunocytochemically using antibodies to a cell surface marker (HNK-1)and acetylated tubulin, and visualized by retrograde and anterograde labeling with a lipophilic dye. The fiber sysytems developed correlating to the organization of the longitudinal and transverse subdivisions of the embryonic brain. The first axons extended from the synencephalic tegmentum, forming the first fiber tract (fasciculus longitudinals medialis) in the ventral longitudinal zone of the neural rod, 38h after fertilization. In the neural tube, throughout the entire brain two pairs of longitudinal fiber systems, one ventral series and one dorsal or intermediate series, and four pairs of transverse fiber tracts in the rostral brain were formed sequentially during the first 16h of axon production. In one of the dorsol longitudinal tracts, its branch retracted and disappeared at later stages.
One of the transverse tracts was found to course in the telencephalon and hypothalamus. The overall pattern of the longitudinal fiber systems in medaka brain is similar to that in mouse, but apparently different from that in zebrafish.
We propose that a ventral tract reported in zebrafish partially belong to the dorsal fiber system, and that the longitudinal fiber systems in all vertebrate brains pass through a common layout defined by conserved genetic and developmental programs., 第１０回　小型魚類研究会},
 title = {Axonogenesis in the medaka embryonic brain},
 year = {2004}
}