@misc{oai:repo.qst.go.jp:00067836,
 author = {Fukuda, Satoshi and Iida, Haruzo and Burgada, Ramon and Bailly, Theodorine and 福田 俊 and 飯田 治三},
 month = {Jul},
 note = {Effects of new two chelating agents, DTPP and CAP, in removing plutonium were compared to those of 3,4,3-LIHOPO (LIHOPO) and Ca-DTPA in rats. Twenty five female Wistar rats, 8 weeks old, were pre-injected with plutonium-239 in the right femoral muscles and divided into five groups; thereafter Rats of four groups were injected intraperitoneally with 30 mmol/kg of DTPP, CAP, LIHOPO or Ca-DTPA respectively, once per day for 3 days, beginning 1 hr after plutonium injection on the first day. The other one group was used a control. On day 4, rats were sacrificed to obtain organs and serum.
   Urinary excretion rate of DTPP was higher, and followed by Ca-DTPA, LIHOPO at the first day and decreased. Feces excretion rate of LIHOPO was higher than other agents for 3 days. CAP had no effect. Total amount of excreted Pu in urine and feces for 3 days of LIHOPO was higher, and followed by Ca-DTPA and DTPP. In the concentration of organs and serum were LIHOPO=DTPP<Ca-DTPA in bone and liver, DTPP<LIHOPO=Ca-DTPA in kidney, DTPP=LIHOPO in serum. 
    The results indicate that LIHOPO was most effective in removing plutonium and DTPP may be worthwhile to examine more in future., 7th International Symposium on Chelating Agents in Biomedicine, Toxicology and therapeutics},
 title = {Effects of DTPP, CAP, LIHOPO and DTPA on Removal of Plutonium in Rats},
 year = {2004}
}