@misc{oai:repo.qst.go.jp:00067639,
 author = {野島, 久美恵 and 長岡, 俊治 and 野島 久美恵 and 長岡 俊治},
 month = {Jul},
 note = {Effects of low dose heavy particle radiation to central nervous system were studied using mouse neonatal brain cells in culture exposed to heavy ions and X ray. The applied dose varied from 0.05Gy to 2.0Gy. The subsequent biological effects were evaluated by an induction of apoptosis and the survivability of neurons focusing on the dependencies of the animal strains with different genetic types, and LET of the different nucleons. Of the three mouse strains tested, SCID, B6 and C3H, for brain cell culture, SCID was the most sensitive and C3H the least sensitive to both X-ray and carbon ion when compared by 10 % apoptotic induction. However, the sensitivity differences among the strains were much smaller in case of carbon ion comparing to that of X-ray. The LET dependency was compared with using C3H and B6 cells exposing to different ions, proton. Although no detectable LET dependency was observed at higher dose than 1 Gy, an enhancement was observed in the high LET and low dose regions. The survivability profiles of the neurons were different in the mouse strains and ions., 第２６回日本神経科学大会},
 title = {Effects of Low Dose Particle Radiation to Mouse Premature Neurons in Culture},
 year = {2003}
}