{"created":"2023-05-15T14:48:40.935008+00:00","id":66692,"links":{},"metadata":{"_buckets":{"deposit":"25a8d4d8-4e6f-434b-844c-a3735391b403"},"_deposit":{"created_by":1,"id":"66692","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"66692"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00066692","sets":["10:29"]},"author_link":["655801","655802","655810","655803","655809","655807","655804","655811","655808","655812","655806","655805"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2016-07-06","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"がん標的分子に結合するRI分子プローブを用いた診断や治療を目指した研究が多く行われている。我々は、がん細胞に過剰発現するHER2タンパクに結合するペプチド(KCCYSL, Lys-Cys-Cys-Tyr-Ser-Leu)に131Iを標識したRI分子プローブの開発を実施している。本発表では、これまで開発してきた“131Iをスズ-ハロゲン交換反応によって標識できるスズフェニルアラニン”をペプチドのN端に導入する合成法を利用したF(p-131I)KCCYSLの合成、細胞結合実験ならびに血清中における安定性について報告する。","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"第53回アイソトープ・放射線研究発表会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"佐々木, 一郎"}],"nameIdentifiers":[{"nameIdentifier":"655801","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"渡辺, 茂樹"}],"nameIdentifiers":[{"nameIdentifier":"655802","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"大島, 康宏"}],"nameIdentifiers":[{"nameIdentifier":"655803","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"須郷, 由美"}],"nameIdentifiers":[{"nameIdentifier":"655804","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"山田, 圭一"}],"nameIdentifiers":[{"nameIdentifier":"655805","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"花岡, 宏史"}],"nameIdentifiers":[{"nameIdentifier":"655806","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"石岡, 典子"}],"nameIdentifiers":[{"nameIdentifier":"655807","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"佐々木 一郎","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"655808","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"渡辺 茂樹","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"655809","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"大島 康宏","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"655810","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"須郷 由美","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"655811","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"石岡 典子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"655812","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"131I標識ペプチドの医学的応用","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"131I標識ペプチドの医学的応用"}]},"item_type_id":"10005","owner":"1","path":["29"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-03-26"},"publish_date":"2018-03-26","publish_status":"0","recid":"66692","relation_version_is_last":true,"title":["131I標識ペプチドの医学的応用"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T20:46:04.179652+00:00"}