{"created":"2023-05-15T14:48:10.954151+00:00","id":66028,"links":{},"metadata":{"_buckets":{"deposit":"fdb07d01-19d7-4df3-bf92-ac8df991d647"},"_deposit":{"created_by":1,"id":"66028","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"66028"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00066028","sets":["10:29"]},"author_link":["776212","776208","776210","776216","776222","776218","776213","776223","776209","776221","776224","776219","776207","776215","776217","776211","776220","776214"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2016-11-05","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Dementia is a severe problem in aging societies. There is a strong potential demand for high-sensitivity, high-resolution, and low-cost brain positron emission tomography (PET) imaging for its early diagnosis. Therefore, we have proposed the helmet-chin PET, a novel geometry for high-sensitivity brain imaging based on a hemispheric arrangement of detectors. For a proof-of-concept, we developed the first prototype using 4-layered depth-of-interaction (DOI) detectors. The helmet-chin PET prototype used 54 DOI detectors, each of which consisted of 16×16×4 Zr-doped GSO crystals (2.8×2.8×7.5 mm3) and a high sensitivity 64-channel flat-panel photomultiplier tube. In the prototype, 47 detectors were used to form a hemisphere of 25 cm inner diameter and 50 cm outer diameter, and 7 detectors were used for the chin detector. In this study, we conducted the first clinical test with a healthy volunteer. First, we compared sensitivity with a whole-body time-of-flight-PET (Biograph mCT Flow 64-4R PET/CT system, Siemens Medical Solutions USA, Inc.) to determine injection activity. As a result, the sensitivity of the helmet-chin PET prototype for the brain region was almost twice as high as that of the mCT, even though the number of detectors was less than 30% that of the mCT. Then a healthy volunteer was measured by the mCT for 15 min beginning 60 min after 18F-FDG injection of 70 MBq and by the helmet-chin PET for 18 min beginning 85 min after the injection. For the first clinical test, we could obtain a clear image of the brain with low radioactivity injection. We analyzed region of interest (ROI) values based on the anatomical structure. As a result, ROI values measured by the helmet-chin PET prototype and the mCT were in good agreement. The first clinical test showed promising performance of the helmet-chin PET for highly sensitive brain imaging.","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"2016 IEEE NSS/MIC","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Tashima, Hideaki"}],"nameIdentifiers":[{"nameIdentifier":"776207","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yoshida, Eiji"}],"nameIdentifiers":[{"nameIdentifier":"776208","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Iwao, Yuma"}],"nameIdentifiers":[{"nameIdentifier":"776209","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Wakizaka, Hidekatsu"}],"nameIdentifiers":[{"nameIdentifier":"776210","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tazawa, Shusaku"}],"nameIdentifiers":[{"nameIdentifier":"776211","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Seki, Chie"}],"nameIdentifiers":[{"nameIdentifier":"776212","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kimura, Yasuyuki"}],"nameIdentifiers":[{"nameIdentifier":"776213","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Suhara, Tetsuya"}],"nameIdentifiers":[{"nameIdentifier":"776214","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamaya, Taiga"}],"nameIdentifiers":[{"nameIdentifier":"776215","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tashima, Hideaki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"776216","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yoshida, Eiji","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"776217","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Iwao, Yuma","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"776218","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Wakizaka, Hidekatsu","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"776219","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tazawa, Shusaku","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"776220","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Seki, Chie","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"776221","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kimura, Yasuyuki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"776222","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Suhara, Tetsuya","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"776223","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamaya, Taiga","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"776224","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"First Clinical Test of the Helmet-Chin PET Prototype","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"First Clinical Test of the Helmet-Chin PET Prototype"}]},"item_type_id":"10005","owner":"1","path":["29"],"pubdate":{"attribute_name":"公開日","attribute_value":"2016-11-22"},"publish_date":"2016-11-22","publish_status":"0","recid":"66028","relation_version_is_last":true,"title":["First Clinical Test of the Helmet-Chin PET Prototype"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-16T00:20:58.185156+00:00"}