{"created":"2023-05-15T14:48:01.197757+00:00","id":65813,"links":{},"metadata":{"_buckets":{"deposit":"ab54d943-e187-46b1-b835-761d05e7b66b"},"_deposit":{"created_by":1,"id":"65813","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"65813"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00065813","sets":["10:29"]},"author_link":["648293","648294","648296","648295","648292","648297"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2015-11-06","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"β線及びα線放出核種で標識した化合物等による治療，即ち標的アイソトープ治療（TargetedRadionuclide Therapy）に関し，近年その研究に注目が集まっている。具体的には131Iの他，90Yや223Raといった治療用核種が臨床利用なされているなか，211Atや64Cuといった候補核種に関する製造・利用報告も多い。今回我々は186Re（T1/2 = 3.72 d, b– 93%, bmax = 1070 keV）の製造を試みた。Reは周期表上，核医学で最も汎用されるTcの下に位置し，その化学的挙動は両者で共通することが多いとされる。従って，従来の核医学が培ってきたTc科学を活用することにより，Reを利用した治療用化合物開発を加速する期待が持たれる。本研究では，濃縮同位体186Wを重陽子で照射することにより186Reを製造し，Tc (Re) に特異的吸着能を持つ2種類の樹脂を利用することで分離を行った。自動化した分離精製装置の開発，並びに収率・純度等の品質結果について報告する。","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"第55回日本核医学会学術総会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"永津, 弘太郎"}],"nameIdentifiers":[{"nameIdentifier":"648292","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"峯岸, 克行"}],"nameIdentifiers":[{"nameIdentifier":"648293","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"張, 明栄"}],"nameIdentifiers":[{"nameIdentifier":"648294","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"永津 弘太郎","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"648295","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"峯岸 克行","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"648296","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"張 明栄","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"648297","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"標的アイソトープ治療用Re-186の製造検討","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"標的アイソトープ治療用Re-186の製造検討"}]},"item_type_id":"10005","owner":"1","path":["29"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-11-19"},"publish_date":"2015-11-19","publish_status":"0","recid":"65813","relation_version_is_last":true,"title":["標的アイソトープ治療用Re-186の製造検討"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T20:55:58.265486+00:00"}