{"created":"2023-05-15T14:47:37.902413+00:00","id":65308,"links":{},"metadata":{"_buckets":{"deposit":"ca35ca72-db0a-4f1a-b32c-56da80f1402b"},"_deposit":{"created_by":1,"id":"65308","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"65308"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00065308","sets":["10:29"]},"author_link":["643576","643574","643572","643575","643573"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2006-07-17","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"我々は、出芽酵母における放射線影響のメカニズムを解析するため、必須遺伝子を\n除く全遺伝子が各々破壊された変異株の集合体であるYeast Deletion Poolを用い\nて、ガンマ線に感受性もしくは耐性となる破壊株のスクリーニングを行った。その結\n果、ガンマ線に感受性になる株として得られた遺伝子の多くは、Cell cycle やDNA修\n復を含む機能別カテゴリーに分類された。一方、耐性株のスクリーニングでは、14株\nのガンマ線耐性株が得られ、それらの株についてDNA障害を引き起こす幾つかの薬剤\nでの耐性を調べた結果、過酸化水素水で野生株に対して耐性の上昇した株、また、\nMMSに対する耐性がわずかに上昇する株等が得られた。そこで、これらの株について\nマイクロアレイを用いた発現解析を行い、遺伝子発現の変化を調べた。今回、これら\nの解析結果について報告する。","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"酵母遺伝学フォーラム第３９回研究報告会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"矢澤, 彌"}],"nameIdentifiers":[{"nameIdentifier":"643572","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"岩崎, 均"}],"nameIdentifiers":[{"nameIdentifier":"643573","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"中島, 徹夫"}],"nameIdentifiers":[{"nameIdentifier":"643574","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"その他"}],"nameIdentifiers":[{"nameIdentifier":"643575","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"中島 徹夫","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"643576","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"出芽酵母遺伝子破壊株を用いた電離放射線耐性株の解析","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"出芽酵母遺伝子破壊株を用いた電離放射線耐性株の解析"}]},"item_type_id":"10005","owner":"1","path":["29"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-11-14"},"publish_date":"2013-11-14","publish_status":"0","recid":"65308","relation_version_is_last":true,"title":["出芽酵母遺伝子破壊株を用いた電離放射線耐性株の解析"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T21:01:35.972741+00:00"}