{"created":"2023-05-15T14:47:35.997832+00:00","id":65265,"links":{},"metadata":{"_buckets":{"deposit":"2edea24a-eee7-4ddd-8970-b272d1cfb639"},"_deposit":{"created_by":1,"id":"65265","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"65265"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00065265","sets":["10:29"]},"author_link":["643130","643118","643121","643122","643124","643128","643127","643126","643120","643119","643129","643125","643117","643123"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2013-11-10","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"【背景・目的】我々のグループでは開放空間も撮像可能なOpenPETの開発を行っており11Cイオンビームを用いることで、重粒子線治療における照射野の可視化を目指している。生体に照射した場合、停止した11Cイオンは拡散(洗い出し)し、この速度から生理パラメータを抽出できる可能性がある。本研究ではこの洗い出し速度を測定した。【方法】 Single-ring OpenPETを用いて、11Cビームを2匹のラットの脳に照射(live)したのち、安楽死させもう一度照射(dead)した。照射直後からの20分のダイナミック撮像を行い、時間放射能曲線(TAC)を算出した。11Cの化学形は分からないが、ウサギに照射した過去の文献から2成分の洗い出し(中間成分k2m、 遅い成分k2s)を考慮したモデルをつくり、洗い出し速度を計算した。【結果・考察】TACから明らかにliveでは、deadより早く減衰しており生理的な影響が見られた。またk2m=0.57min-1、k2s=0.017 min-1であった。この洗い出し速度の解釈については今後の課題であるが、H215O-PETにおける脳血流測定の動態解析の結果と同程度の値だった。","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"第５３回日本核医学学術総会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"平野, 祥之"}],"nameIdentifiers":[{"nameIdentifier":"643117","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"吉田, 英治"}],"nameIdentifiers":[{"nameIdentifier":"643118","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"脇坂, 秀克"}],"nameIdentifiers":[{"nameIdentifier":"643119","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"中島, 靖紀"}],"nameIdentifiers":[{"nameIdentifier":"643120","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"錦戸, 文彦"}],"nameIdentifiers":[{"nameIdentifier":"643121","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"伊藤, 浩"}],"nameIdentifiers":[{"nameIdentifier":"643122","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"山谷, 泰賀"}],"nameIdentifiers":[{"nameIdentifier":"643123","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"平野 祥之","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"643124","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"吉田 英治","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"643125","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"脇坂 秀克","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"643126","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"中島 靖紀","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"643127","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"錦戸 文彦","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"643128","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"伊藤 浩","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"643129","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"山谷 泰賀","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"643130","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"OpenPETを用いたラットへのRIビーム照射における11Cイオン動態解析の試み","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"OpenPETを用いたラットへのRIビーム照射における11Cイオン動態解析の試み"}]},"item_type_id":"10005","owner":"1","path":["29"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-11-13"},"publish_date":"2013-11-13","publish_status":"0","recid":"65265","relation_version_is_last":true,"title":["OpenPETを用いたラットへのRIビーム照射における11Cイオン動態解析の試み"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T21:02:06.343642+00:00"}