{"created":"2023-05-15T14:47:30.161004+00:00","id":65134,"links":{},"metadata":{"_buckets":{"deposit":"b663900c-fe4a-48b2-94eb-a18cbe0985a4"},"_deposit":{"created_by":1,"id":"65134","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"65134"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00065134","sets":["10:29"]},"author_link":["641736","641727","641728","641730","641729","641735","641739","641732","641724","641737","641726","641725","641734","641731","641733","641738"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2013-09-14","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"【目的】前立腺癌に対して重粒子線治療を行った症例において、治療後5年までのQOLの変化について前向き調査を行い、結果を検討した。\n\\n【方法】当院の前立腺癌治療プロトコールで2000年4月〜2007年1月に重粒子線治療を行い、5年間経過観察を行った患者417例を対象とした。年齢中央値は69歳（47-92）、リスク分類は低リスク79例、中リスク86例、高リスク252例。中、高リスク症例はそれぞれ短期、長期のホルモン療法を併用し、処方線量は63GyE〜66GyE/20回/5週を用いた。\n治療前後のQOL調査はFACT-P調査票（日本語版 ver.4）を用い、治療前、1ヶ月後（治療終了時）、1年後、3年後、5年後の各時点において評価した。再発や晩期有害事象の有無とQOL スコアの関連についても検討した。\n\\n【結果】全例で予定の重粒子線治療を完遂した。全症例のbRFSは5年89.9％、CSSは5年98.3％、OSは5年94.5％であった。RTOG/EORTC Grade 3の晩期有害事象（膀胱出血）を1例に認めたが、その他はGrade 2以下であった。FACT-P調査票の回収率は全体で95.0％であった。FACT-Pスコアは治療前と比べ治療終了時以降で有意な低下を認め、FACT-Gスコアは治療後3年以降で有意に低下した。FACT-TOI （Trial outcome index）スコアは治療終了時で有意に低下したが、その後スコアは回復し1年後以降有意差は消失した。再発や晩期有害事象（G1以上）のある群では、ない群と比較しスコアが低い傾向が認められた。\n\\n【結論】前立腺癌重粒子線治療症例を対象に長期の前向き調査を行い、高いコンプライアンスのもとで重粒子線治療後の良好なQOLの維持が確認された。","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"第10回　日本粒子線治療臨床研究会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"丸山, 克也"}],"nameIdentifiers":[{"nameIdentifier":"641724","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"辻, 比呂志"}],"nameIdentifiers":[{"nameIdentifier":"641725","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"野宮, 琢磨"}],"nameIdentifiers":[{"nameIdentifier":"641726","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"若月, 優"}],"nameIdentifiers":[{"nameIdentifier":"641727","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"加藤, 弘之"}],"nameIdentifiers":[{"nameIdentifier":"641728","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"石川, 仁"}],"nameIdentifiers":[{"nameIdentifier":"641729","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"青山, 英史"}],"nameIdentifiers":[{"nameIdentifier":"641730","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鎌田, 正"}],"nameIdentifiers":[{"nameIdentifier":"641731","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"丸山 克也","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"641732","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"辻 比呂志","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"641733","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"野宮 琢磨","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"641734","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"若月 優","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"641735","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"加藤 弘之","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"641736","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"石川 仁","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"641737","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"青山 英史","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"641738","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鎌田 正","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"641739","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"前立腺癌に対する重粒子線治療後のＱＯＬ評価","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"前立腺癌に対する重粒子線治療後のＱＯＬ評価"}]},"item_type_id":"10005","owner":"1","path":["29"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-09-17"},"publish_date":"2013-09-17","publish_status":"0","recid":"65134","relation_version_is_last":true,"title":["前立腺癌に対する重粒子線治療後のＱＯＬ評価"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T21:03:39.465213+00:00"}