{"created":"2023-05-15T14:47:11.226352+00:00","id":64709,"links":{},"metadata":{"_buckets":{"deposit":"dcd188dd-2526-40db-ab32-b0c3a4141ef3"},"_deposit":{"created_by":1,"id":"64709","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"64709"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00064709","sets":["10:29"]},"author_link":["637618","637623","637628","637619","637622","637620","637621","637624","637626","637630","637631","637632","637617","637629","637627","637625"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2012-09-08","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"胸部放射線治療における重篤な晩期障害である放射線肺炎および肺線維症は、治療後のQOLを考える上で解決すべき課題の一つである。我々はこれまで、炭素イオン線照射による肺線維化の発症にマウス系統差があること、さらにその原因と考えられる系統間での遺伝子発現の違いを報告してきた。近年、損傷した肺と骨髄の関係に特に治癒の面から関心が高まっている。そこで我々が解析を行っている肺晩発マウスモデルにおいて、骨髄への影響についても検討を行った。\n炭素イオン線 (290MeV/n, SOBP) 10Gyを2系統のマウス (C57Bl/6J, C3H/He)の胸部に照射し、経時的に観察を行った。照射後、照射野に入っていなかった大腿骨骨髄中に巨核球細胞の顕著な増加が認められた。さらに、赤芽球系細胞の島状の増殖と細胞死の増加が骨髄中で観察された。これらの結果は、実際に照射されていない大腿骨中の骨髄も、胸部局所照射の影響を大きく受けている事を示すものである。本学会では炭素線胸部照射後の骨髄中の変化について報告する。","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"日本放射線影響学会第55回大会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"下川, 卓志"}],"nameIdentifiers":[{"nameIdentifier":"637617","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"小久保, 年章"}],"nameIdentifiers":[{"nameIdentifier":"637618","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"中渡, 美也子"}],"nameIdentifiers":[{"nameIdentifier":"637619","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"藤田, 英俊"}],"nameIdentifiers":[{"nameIdentifier":"637620","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"佐藤, 克俊"}],"nameIdentifiers":[{"nameIdentifier":"637621","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"中村, 悦子"}],"nameIdentifiers":[{"nameIdentifier":"637622","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"森竹, 浩之"}],"nameIdentifiers":[{"nameIdentifier":"637623","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"今井, 高志"}],"nameIdentifiers":[{"nameIdentifier":"637624","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"下川 卓志","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"637625","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"小久保 年章","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"637626","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"中渡 美也子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"637627","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"藤田 英俊","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"637628","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"佐藤 克俊","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"637629","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"中村 悦子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"637630","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"森竹 浩之","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"637631","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"今井 高志","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"637632","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"炭素イオン線胸部局所照射による肺線維化マウスモデルにおける骨髄への影響","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"炭素イオン線胸部局所照射による肺線維化マウスモデルにおける骨髄への影響"}]},"item_type_id":"10005","owner":"1","path":["29"],"pubdate":{"attribute_name":"公開日","attribute_value":"2012-09-10"},"publish_date":"2012-09-10","publish_status":"0","recid":"64709","relation_version_is_last":true,"title":["炭素イオン線胸部局所照射による肺線維化マウスモデルにおける骨髄への影響"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T21:08:32.317420+00:00"}