{"created":"2023-05-15T14:47:07.136794+00:00","id":64617,"links":{},"metadata":{"_buckets":{"deposit":"b9acec73-b0e9-4b00-b449-8eab2857fe06"},"_deposit":{"created_by":1,"id":"64617","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"64617"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00064617","sets":["10:29"]},"author_link":["636811","636813","636809","636805","636808","636812","636814","636810","636816","636806","636817","636818","636815","636807"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2012-06-08","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"目的】腺癌のＸ線治療感受性は扁平上皮癌に比して低いため、鼻・副鼻腔腺癌の手術不能例では長期予後が期待できないだけでなく、機能、整容面で患者のQOLは大幅に低下する。重粒子線はＸ線と比較して高い抗腫瘍効果と線量集中により、鼻・副鼻腔腺癌の根治治療法となる可能性がある。今回鼻・副鼻腔腺癌の重粒子線治療成績を評価した。\n\\n【対象・方法】対象は1997年6月〜2010年1月に重粒子線治療が施行された鼻・副鼻腔腺癌22例（男性11例、女性11例、年齢中央値は61歳）。原発部位は鼻腔6例、篩骨洞11例、上顎洞5例。初回治療例は17例、術後再発3例、術後残存1例、化学療法後残存1例であった。治療開始時のT分類はT2：1例、T3:1例、T4a:6、T4b:14であった。炭素イオン線治療は16回/4週のスケジュールで行われ、14例は57.6GyE、8例は64.0GyEで治療された。\n\\n【結果】全例治療を完遂した。全症例の観察期間中央値は34ヵ月(4-126ヵ月)。生存例10例の観察期間中央値は59ヵ月。5年局所（照射野内）制御率は73.4％であった。5年全生存率、原病生存率、無病生存率はそれぞれ56.7％、62.9％、43.8%。晩期のGrade3以上の有害事象として視神経炎4例、腐骨1例、粘膜潰瘍1例を高線量域内に認めた。\n\\n【結論】重粒子線治療は鼻・副鼻腔腺癌に対して有効な治療法であり、手術不能症例に対しても長期予後、QOLの維持が期待できる。","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"第３６回日本頭頸部癌学会　","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"小藤, 昌志"}],"nameIdentifiers":[{"nameIdentifier":"636805","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"長谷川, 安都佐"}],"nameIdentifiers":[{"nameIdentifier":"636806","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"高木, 亮"}],"nameIdentifiers":[{"nameIdentifier":"636807","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"藤川, 陽"}],"nameIdentifiers":[{"nameIdentifier":"636808","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"松本, 圭司"}],"nameIdentifiers":[{"nameIdentifier":"636809","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"森川, 貴迪"}],"nameIdentifiers":[{"nameIdentifier":"636810","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鎌田, 正"}],"nameIdentifiers":[{"nameIdentifier":"636811","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"小藤 昌志","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"636812","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"長谷川 安都佐","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"636813","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"高木 亮","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"636814","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"藤川 陽","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"636815","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"松本 圭司","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"636816","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"森川 貴迪","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"636817","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鎌田 正","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"636818","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"局所進行鼻・副鼻腔腺癌に対する重粒子線治療","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"局所進行鼻・副鼻腔腺癌に対する重粒子線治療"}]},"item_type_id":"10005","owner":"1","path":["29"],"pubdate":{"attribute_name":"公開日","attribute_value":"2012-06-11"},"publish_date":"2012-06-11","publish_status":"0","recid":"64617","relation_version_is_last":true,"title":["局所進行鼻・副鼻腔腺癌に対する重粒子線治療"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T21:09:34.206228+00:00"}