@misc{oai:repo.qst.go.jp:00064583, author = {Tsujii, Hirohiko and 辻井 博彦}, month = {Apr}, note = {In cancer radiotherapy (RT), ion beams such as proton and carbon ion beams have unique characteristics of improved dose distributions, enabling a delivery of sufficient dose to the target volume while minimizing the dose in the surrounding normal tissues. In addition, carbon ions being heavier than protons provide a higher biological effectiveness with increasing the depth, reaching the maximum at the end of the beam's range (1,2). Over the last decade, carbon ion RT has been applied to a number of tumors that are difficult to control with other modalities, and the number of facilities has been also increased worldwide. In these facilities including National Institute of Radiological Sciences (NIRS) in Japan and Gesellschaft fur Schwerionenforschung (GSI) in Germany, clinical study has been focused on an attempt to identify tumor sites suitable for carbon ion therapy and to determine the optimal dose-fractionation and irradiation methods (3-8)., New Frontiers in Cancer Treatment: A Focus on Photon and Carbon Ion Radiation Therapy}, title = {Overview of carbon ion radiotherapy}, year = {2012} }