{"created":"2023-05-15T14:46:47.657390+00:00","id":64199,"links":{},"metadata":{"_buckets":{"deposit":"86d310f6-6a93-45ed-803e-06c012f1776f"},"_deposit":{"created_by":1,"id":"64199","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"64199"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00064199","sets":["10:29"]},"author_link":["633160","633157","633151","633159","633146","633150","633155","633154","633158","633148","633156","633152","633147","633153","633149"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2010-11-20","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"【目的】本邦の早期子宮頸癌に対する高線量率腔内照射（HDR-ICBT）を用いた根治的放射線治療標準的治療スケジュールの安全性と有効性を探索的に検討する。\n\\n【方法】I,II期子宮頸癌扁平上皮癌、腫瘍最大径40mm未満（MRI T2強調像）を対象とした。全骨盤照射50Gy/25回（中央遮蔽20Gy/10回後）+HDR-ICBT 24Gy/4回（A点）を試験治療とした（BED 62Gy10）。目標症例数は60例（3年間）で、追跡機関は最終症例登録後2年とした。主要評価項目は2年骨盤内無増悪割合とした。\n\\n【結果】2004年9月−7月に13施設より予定60例が登録された。年齢中央値は73才（37-84才）、Ib:36例、IIa:12例、IIb:12例、腫瘍最大径中央値29mm(6-39mm)であった。全例試験治療を完遂し、総治療期間中央値43日（38-55日）であった。観察期間中央値38ヶ月7-57ヶ月）で、初回再発部位は骨盤内3例（子宮2例、骨盤リンパ節1例）、骨盤外4例であった。2年骨盤内無増悪割合/全生存割合は、96%（95% CI,92%-100%）95%(95% CI,89%-100%）であった。直腸出血11例、膀胱出血1例、小腸障害4例を認めたが、グレード3（RTOG/EORTC基準）以上は無かった。\n\\n【結論】早期子宮頸癌に対し、本邦標準的治療スケジュールによるHDR-ICBTを用いた根治的放射線治療（BED62Gy10）は安全かつ有効であることが示唆された。","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"日本放射線腫瘍学会第23回学術大会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"戸板, 孝文"}],"nameIdentifiers":[{"nameIdentifier":"633146","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"加藤, 真吾"}],"nameIdentifiers":[{"nameIdentifier":"633147","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"新部, 譲"}],"nameIdentifiers":[{"nameIdentifier":"633148","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"大野, 達也"}],"nameIdentifiers":[{"nameIdentifier":"633149","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"楮本, 智子"}],"nameIdentifiers":[{"nameIdentifier":"633150","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"古平, 毅"}],"nameIdentifiers":[{"nameIdentifier":"633151","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"片岡, 正明"}],"nameIdentifiers":[{"nameIdentifier":"633152","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"手島, 昭樹"}],"nameIdentifiers":[{"nameIdentifier":"633153","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"小口, 正彦"}],"nameIdentifiers":[{"nameIdentifier":"633154","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"加賀美, 芳和"}],"nameIdentifiers":[{"nameIdentifier":"633155","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"加藤 眞吾","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"633156","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"大野 達也","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"633157","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"古平 毅","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"633158","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"手島 昭樹","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"633159","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"小口 正彦","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"633160","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"I, II期子宮頸癌根治的放射線治療の多施設共同臨床研究（JAROG0401/JROSGS04-2)","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"I, II期子宮頸癌根治的放射線治療の多施設共同臨床研究（JAROG0401/JROSGS04-2)"}]},"item_type_id":"10005","owner":"1","path":["29"],"pubdate":{"attribute_name":"公開日","attribute_value":"2011-02-01"},"publish_date":"2011-02-01","publish_status":"0","recid":"64199","relation_version_is_last":true,"title":["I, II期子宮頸癌根治的放射線治療の多施設共同臨床研究（JAROG0401/JROSGS04-2)"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T21:14:20.066866+00:00"}