@misc{oai:repo.qst.go.jp:00064162,
 author = {安田, 茂雄 and 加藤, 博敏 and 今田, 浩史 and 鎌田, 正 and 安田 茂雄 and 加藤 博敏 and 今田 浩史 and 鎌田 正},
 month = {Apr},
 note = {The purpose of this study is to analyze the correlation between hepatic toxicities and dose-volume factors of carbon ion radiotherapy in patients with hepatocellular carcinoma (HCC). Fifty patients received carbon ion radiotherapy with a total dose of 52.8GyE delivered in 4 fractions over 4 to 7days. The correlation between various blood biochemistry data and dose-volume histogram (DVH) parameters in non-cancerous liver was analyzed. The strongest significant correlation was seen between the volume of non-cancerous liver which received equal or higher than 11GyE (V11GyE ) and elevation of serum GOT level as a early adverse response after carbon ion beam radiation therapy (p=0.0003). In addition, significant correlations between dose volume data and change of several other blood biochemistry data were also revealed in early phase. In late phase after carbon ion radiotherapy, the strongest significant correlation was seen between decrease of platelet count and V26GyE (p=0.015). There was no significant correlation between the other blood biochemistry data and dose volume data in the late phase. It was thought that the risk of the liver toxicities after carbon ion radiotherapy could be predicted by the analysis of dose-volume data., 平成20年度HIMAC共同利用研究成果発表会},
 title = {肝細胞癌の炭素イオン線治療における有害反応のDVH解析},
 year = {2009}
}