@misc{oai:repo.qst.go.jp:00064105, author = {神宮, 啓一 and 溝江, 純悦 and 長谷川, 安都佐 and 別所, 央城 and 吉川, 京燦 and 岸本, 理和 and 神宮 啓一 and 溝江 純悦 and 長谷川 安都佐 and 別所 央城 and 吉川 京燦 and 岸本 理和}, month = {Apr}, note = {Abstract [Purpose] to evaluate the potential of apparent diffusion coefficient (ADC) value before carbon ion radiotherapy for mucosal malignant melanoma to predict the prognosis [Materials and methods] We recruited patients with mucosal malignant melanoma of the head and neck who were treated by carbon ion radiotherapy with concomitant chemotherapy, and analyzed retrospectively. All patients were performed carbon ion radiotherapy with 57.6GyE/16fr. with concurrent chemotherapy (DAV). Distant metastasis-free survival rate and overall survival were calculated with Kaplan-Meier method. [Results] Thirty-seven patients were enrolled. Median follow-up period was 19.3 months. The 3-year distant metastasis-free survival rate and overall survival rate of all patients were 40.7% and 81.2%, respectively. Distant metastasis-free survival rate and overall survival rate of the patients with lower minimum ADC were significant worse than those of the patients with higher minimum ADC (log-rank test, p=0.004 and p=0.02, respectively). [Conclusion] Minimum ADC might be a prognostic factor of distant metastasis and overall survival of mucosal malignant melanoma of the head and neck., H21年度HIMAC共同利用研究成果発表会}, title = {粘膜悪性黒色腫重粒子線治療における機能画像による予後予測解析}, year = {2010} }