{"created":"2023-05-15T14:46:43.360953+00:00","id":64102,"links":{},"metadata":{"_buckets":{"deposit":"a90e83cc-f74c-4a15-80eb-1f3fe4795f10"},"_deposit":{"created_by":1,"id":"64102","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"64102"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00064102","sets":["10:29"]},"author_link":["632327","632331","632324","632328","632325","632332","632326","632330","632329","632333"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2010-11-13","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Aim:To evaluate the changes in dopamine (DA) synthesis capacity before and after antipsychotic treatment in patients with schizophrenia.\nMethod:Twelve patients underwent positron emission tomography studies with [11C]DOPA before (baseline) and 1 day after treatment with antipsychotic drug, risperidone. DA synthesis capacity, ki, was determined for the striatum using a graphical plot analysis method and with the occipital cortex as a reference region.\nResult:Patients showed no significant unidirectional change in DA synthesis capacity before and after risperidone administration; However, a significant negative correlation was observed between the baseline ki value and the change rate of ki before and after risperidone administration (r = -0.63, p = 0.029).\nConclusion:These findings might be indicative of a stabilizing effect of risperidone to the presynaptic DA function.","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"第50回日本核医学会学術総会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"高野, 晴成"}],"nameIdentifiers":[{"nameIdentifier":"632324","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"伊藤, 浩"}],"nameIdentifiers":[{"nameIdentifier":"632325","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"荒川, 亮介"}],"nameIdentifiers":[{"nameIdentifier":"632326","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"高橋, 英彦"}],"nameIdentifiers":[{"nameIdentifier":"632327","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"須原, 哲也"}],"nameIdentifiers":[{"nameIdentifier":"632328","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"高野 晴成","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"632329","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"伊藤 浩","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"632330","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"荒川 亮介","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"632331","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"高橋 英彦","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"632332","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"須原 哲也","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"632333","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"統合失調症における抗精神病薬前後でのドーパミン生成能の変化","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"統合失調症における抗精神病薬前後でのドーパミン生成能の変化"}]},"item_type_id":"10005","owner":"1","path":["29"],"pubdate":{"attribute_name":"公開日","attribute_value":"2010-11-16"},"publish_date":"2010-11-16","publish_status":"0","recid":"64102","relation_version_is_last":true,"title":["統合失調症における抗精神病薬前後でのドーパミン生成能の変化"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T21:15:24.605007+00:00"}