@misc{oai:repo.qst.go.jp:00064075,
 author = {Shimada, Yoshiya and Kakinuma, Shizuko and Nishimura, Mayumi and Yamada, Yutaka and Imaoka, Tatsuhiko and Takabatake, Takashi and Takeda, Shino and Shang, Yi and Amasaki, Yoshiko and Hirano, Shinobu and Sawai, Tomoko and Daino, Kazuhiro and Kawaguchi, Isao and Saigusa, Shin and 島田 義也 and 柿沼 志津子 and 石田 有香 and 山田 裕 and 西村 まゆみ and 高畠 貴志 and 武田 志乃 and 尚 奕 and 甘崎 佳子 and 坂入 しのぶ and 澤井 知子 and 臺野 和広 and 川口 勇生 and 三枝 新},
 month = {Oct},
 note = {The Japanese Radiobiology Archives (JRA) has been constructed by the leadership of Dr. Shin Saigusa, NIRS, to assemble and catalogue the data of animal experiments conducted for these 30 years in Japan.  Recent rapid progress of molecular technologies of small piece of samples has enabled us to add the new findings from the past experiments, which are hardly repeated for the financial and ethical reasons. One of successful example is the experiment of mouse thymic lymphomas after combined exposure to X-rays with ENU, which are re-examined to establish the mathematical model of combined effects of carcinogenesis (Kawaguchi et al., 2006).  The other example is a discovery of human type EGFR mutation in rat lung tumors induced by X-rays, which have not been found in rodent lung tumors induced by several chemical carcinogens (Kitahashi et al., 2008).  From these points of views, European Commission and U.S. DOE have sponsored to promote radiobiology archives to collect the data such as mortality, autopsy records, paraffin-embedded tissue, and microscope slide.  In the next few years, we are attempting to construct an integrated data network facilitated by internet web.  For the time being, images of histopathology need to be automatically linked to their data records, by which the researcher can communicate by filling in/out their comments on the web page.  This is especially important for the studies using Pu and U, which are not allowed to bring out from the facility.  JRA will collaborate with European RA (ERA) and U.S. RA (NRA) to form the worldwide archives., 日本放射線影響学会第53回大会},
 title = {Construction and Utization of Radiobiological Archives of NIRS},
 year = {2010}
}