{"created":"2023-05-15T14:46:38.406963+00:00","id":63992,"links":{},"metadata":{"_buckets":{"deposit":"9ec5bd4a-7202-4012-a2da-ab1387902848"},"_deposit":{"created_by":1,"id":"63992","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"63992"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00063992","sets":["10:29"]},"author_link":["631378","631367","631376","631371","631374","631369","631379","631366","631375","631372","631377","631373","631370","631368"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2010-09-11","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"1. Skull Base and Paracervical Tumors\nAbstract\nTo estimate the toxicity and efficacy of the clinical trials for patients with skull base and paracervical tumors treated with carbon ion radiotherapy.\nA phase I/II dose escalation study for skull base and paracervical tumor was initiated in April 1997. The phase I/II dose escalation trial was performed up to the fourth-stage dose level. From April 2004, a phase II clinical trial was initiated under the Highly Advanced Medical Technology scheme with an irradiation schedule of 60.8 GyE in 16 fractions over four weeks.\nAt the time of analysis, there was no evidence of any serious acute or late reactions in skull base and paracervical tumors. For skull base and paracervical tumor, the carbon ion dose in excess of 57.6 GyE improves local control. \n\\n2. Head-and-Neck Tumors\nAbstract\nTo evaluate the efficacy of carbon ion radiotherapy for malignant head-and-neck tumors.\nBetween April 1997 and February 2010, 378 cases with locally advanced, histologically proven, and new or recurrent malignant tumors of the head-and-neck were treated with carbon ions. Treatment dose was 64.0 GyE in 16 fractions over 4 weeks (or 57.6 GyE when a wide area of skin was included in the target volume).\nThere were no acute reactions worse than grade 3 and no late toxicities worse than grade 2. The five-year local control and overall survival rates were 75% and 54%, respectively. But the five-year local control rate was 25% for bone and soft tissue sarcomas, and the five-year overall survival rate was 36% for malignant melanomas. \nCarbon ion radiotherapy for malignant head-and-neck tumors can be described as presenting no clinical problems. Although local control of carbon ion radiotherapy was promising for malignant head-and-neck tumor excluding sarcoma, the survival rate was not commensurate with the favorable local control rate of malignant melanoma. On the basis of the results of the analysis, this part of the study was divided into two additional protocols, one for bone and soft tissue sarcomas and another for mucosal malignant melanomas.","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"The 4th Japanese-European Joint Symposium on Ion Cancer Therapy","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Hasegawa, Azusa"}],"nameIdentifiers":[{"nameIdentifier":"631366","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Koto, Masashi"}],"nameIdentifiers":[{"nameIdentifier":"631367","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Takagi, Ryo"}],"nameIdentifiers":[{"nameIdentifier":"631368","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Morikawa, Takamichi"}],"nameIdentifiers":[{"nameIdentifier":"631369","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kamada, Tadashi"}],"nameIdentifiers":[{"nameIdentifier":"631370","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Mizoe, Junetsu"}],"nameIdentifiers":[{"nameIdentifier":"631371","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tsujii, Hirohiko"}],"nameIdentifiers":[{"nameIdentifier":"631372","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"長谷川 安都佐","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"631373","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"小藤 昌志","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"631374","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"高木 亮","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"631375","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"森川 貴迪","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"631376","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鎌田 正","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"631377","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"溝江 純悦","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"631378","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"辻井 博彦","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"631379","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"Carbon Ion Radiotherapy for Skull Base and Head-and-Neck Tumors","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Carbon Ion Radiotherapy for Skull Base and Head-and-Neck Tumors"}]},"item_type_id":"10005","owner":"1","path":["29"],"pubdate":{"attribute_name":"公開日","attribute_value":"2010-09-13"},"publish_date":"2010-09-13","publish_status":"0","recid":"63992","relation_version_is_last":true,"title":["Carbon Ion Radiotherapy for Skull Base and Head-and-Neck Tumors"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T21:16:39.475615+00:00"}