@misc{oai:repo.qst.go.jp:00063955, author = {Konishi, Teruaki and Oikawa, Masakazu and Iso, Hiroyuki and Ishikawa, Takahiro and Higuchi, Yuichi and Suya, Noriyoshi and Isono, Mayu and Choi, Viann and Yu, Peter and Yasuda, Nakahiro and Kodama, Kumiko and Maeda, Takeshi and Imaseki, Hitoshi and 小西 輝昭 and 及川 将一 and 磯 浩之 and 石川 剛弘 and 樋口 有一 and 酢屋 徳啓 and 安田 仲宏 and 児玉 久美子 and 前田 武 and 今関 等}, month = {Jul}, note = {Single-cell microbeam irradiation systems have become significant tools in the field of radiation biology. Recently, many microbeam facilities have been developed, and are available for biological research. Also in Japan, there are many microbeam facilities with different types of radiation sources that are now available for biological studies [Kobayashi, 2009]. Single particle irradiation system to cell, SPICE [Konishi, 2009] at National Institute of Radiological Sciences (NIRS), generates 3.4 MeV protons with an approximately 2 um beam and are successful in targeting individual cells and delivering specified number of protons to targeted cells. SPICE is currently operated for low-dose effects studies, including hyper radio-sensitivity, bystander effects studies using cells., 9th International Microbeam Workshop}, title = {Current status of single particle irradiation system to cell SPICE at NIRS}, year = {2010} }