{"created":"2023-05-15T14:46:33.508807+00:00","id":63883,"links":{},"metadata":{"_buckets":{"deposit":"87d88b1d-3a82-4ded-8c88-883ce115b86b"},"_deposit":{"created_by":1,"id":"63883","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"63883"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00063883","sets":["10:29"]},"author_link":["630281","630280","630284","630272","630282","630277","630274","630283","630275","630278","630271","630276","630273","630279"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2010-04-20","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"【目的】マウス晩期障害実験モデルを用いて、炭素線治療後の有害事象発症メカニズムを明らかにする。\n【材料と方法】炭素線10Gy (290 MeV/nucleon, 3Gy/min, 6 cm SDBP) を照射した。炭素線照射後の肺組織、膀胱組織を組織学的に解析した。炭素線照射に応答する分子を明らかにするため、炭素線照射後６時間のRNAを用いて遺伝子発現解析を行った。\n【結果】炭素線照射後、C3H/He において、亜急性期に、また、C57BL/6J においては晩期に肺傷害が認められた。マイクロアレイ解析により、炭素線照射による発現に系統差がある遺伝子が明らかになり、免疫染色学的解析により、膀胱内組織染色の系統差が認められた。","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"HIMAC共同利用研究 成果発表会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"藤田, 英俊"}],"nameIdentifiers":[{"nameIdentifier":"630271","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"岩川, 眞由美"}],"nameIdentifiers":[{"nameIdentifier":"630272","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"辻, 比呂志"}],"nameIdentifiers":[{"nameIdentifier":"630273","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"中村, 悦子"}],"nameIdentifiers":[{"nameIdentifier":"630274","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"酒井, 美奈子"}],"nameIdentifiers":[{"nameIdentifier":"630275","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"柳澤, 充"}],"nameIdentifiers":[{"nameIdentifier":"630276","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"今井, 高志"}],"nameIdentifiers":[{"nameIdentifier":"630277","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"藤田 英俊","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"630278","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"岩川 眞由美","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"630279","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"辻 比呂志","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"630280","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"中村 悦子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"630281","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"酒井 美奈子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"630282","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"柳澤 充","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"630283","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"今井 高志","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"630284","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"晩期障害マウスモデルを用いた重粒子線治療有害事象","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"晩期障害マウスモデルを用いた重粒子線治療有害事象"}]},"item_type_id":"10005","owner":"1","path":["29"],"pubdate":{"attribute_name":"公開日","attribute_value":"2010-05-13"},"publish_date":"2010-05-13","publish_status":"0","recid":"63883","relation_version_is_last":true,"title":["晩期障害マウスモデルを用いた重粒子線治療有害事象"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T21:17:55.496416+00:00"}