{"created":"2023-05-15T14:46:31.957919+00:00","id":63852,"links":{},"metadata":{"_buckets":{"deposit":"7e9af775-4765-4998-b170-1e389a748cca"},"_deposit":{"created_by":1,"id":"63852","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"63852"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00063852","sets":["10:29"]},"author_link":["629933","629922","629924","629920","629943","629925","629936","629937","629944","629946","629926","629949","629927","629928","629931","629942","629938","629945","629921","629950","629929","629930","629919","629941","629934","629935","629940","629939","629947","629932","629948","629923"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2010-03-17","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"世界規模のバイオリソース事業の発展により、放医研においても凍結保存胚を用いた新規マウス導入が増えつつある。しかしながら、本所の発生工学ラボが、衛生上CVレベルにあること、導入される凍結胚数が20-40個と少ないことからSPF施設へのマウス供給を凍結胚移植した受容雌の帝王切開にて直接行うには低蘇生率、哺育時高食殺率のリスクが高すぎ、実用化は困難である。それ故、CVレベルにて凍結胚由来産仔が成熟した後に体外受精−移植法を行い、多数の胚を移植後に帝王切開法にて清浄化しているが、導入から供給まで最短でも２３週間（約半年）の長期間を要する。\n今回、新規凍結胚導入動物（ATM-KOマウス）の供給期間を短縮すべく、凍結胚由来の若齢雌を用いることにより17週間（約4ヶ月）にてSPFレベルに迅速に動物導入することを可能にした。さらに、この方法により衛生検査・飼育作業の短縮・低減化など業務の効率化にも貢献出来た。","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"第５回技術と安全の報告会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"鬼頭, 靖司"}],"nameIdentifiers":[{"nameIdentifier":"629919","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"太田, 有紀"}],"nameIdentifiers":[{"nameIdentifier":"629920","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"和田, 彩子"}],"nameIdentifiers":[{"nameIdentifier":"629921","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"林, 真美"}],"nameIdentifiers":[{"nameIdentifier":"629922","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"矢野, 浩子"}],"nameIdentifiers":[{"nameIdentifier":"629923","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"石井, 洋子"}],"nameIdentifiers":[{"nameIdentifier":"629924","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"新妻, 大介"}],"nameIdentifiers":[{"nameIdentifier":"629925","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"石原, 直樹"}],"nameIdentifiers":[{"nameIdentifier":"629926","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"伊藤, 正人"}],"nameIdentifiers":[{"nameIdentifier":"629927","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"塚本, 智史"}],"nameIdentifiers":[{"nameIdentifier":"629928","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"上野, 渉"}],"nameIdentifiers":[{"nameIdentifier":"629929","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"石田, 有香"}],"nameIdentifiers":[{"nameIdentifier":"629930","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"小久保, 年章"}],"nameIdentifiers":[{"nameIdentifier":"629931","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"河合, 直士"}],"nameIdentifiers":[{"nameIdentifier":"629932","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"西川, 哲"}],"nameIdentifiers":[{"nameIdentifier":"629933","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"酒井, 一夫"}],"nameIdentifiers":[{"nameIdentifier":"629934","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鬼頭 靖司","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"629935","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"太田 有紀","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"629936","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"和田 彩子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"629937","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"林 真美","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"629938","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"矢野 浩子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"629939","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"石井 洋子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"629940","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"新妻 大介","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"629941","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"石原 直樹","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"629942","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"伊藤 正人","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"629943","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"塚本 智史","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"629944","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"上野 渉","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"629945","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"石田 有香","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"629946","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"小久保 年章","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"629947","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"河合 直士","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"629948","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"西川 哲","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"629949","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"酒井 一夫","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"629950","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"新規凍結胚導入マウス清浄化の短縮−若齢雌での発生工学手法の応用−","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"新規凍結胚導入マウス清浄化の短縮−若齢雌での発生工学手法の応用−"}]},"item_type_id":"10005","owner":"1","path":["29"],"pubdate":{"attribute_name":"公開日","attribute_value":"2010-03-24"},"publish_date":"2010-03-24","publish_status":"0","recid":"63852","relation_version_is_last":true,"title":["新規凍結胚導入マウス清浄化の短縮−若齢雌での発生工学手法の応用−"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T21:18:16.401021+00:00"}