{"created":"2023-05-15T14:46:26.648959+00:00","id":63734,"links":{},"metadata":{"_buckets":{"deposit":"4c00239e-8a3c-44f5-8b4a-a377744aad28"},"_deposit":{"created_by":1,"id":"63734","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"63734"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00063734","sets":["10:29"]},"author_link":["629053","629055","629059","629051","629052","629060","629054","629056","629057","629058"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2009-10-03","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"放射線治療ではしばしば骨髄が照射野に含まれる。FLTは増殖のマーカーとされ、FLT-PETでは正常骨髄が描画される。骨髄の放射線照射による変化のFLTでの評価を検討した。重粒子放射線治療を受けた肺癌患者21例に、FLT-PET/CTを治療前、治療直後、3カ月後、１年以上後に施行した。治療は、42-44 GyE/1回、52.8−60 GyE/4回分割、62.8GyE/12回であった。照射野内および照射野外（腰椎）の骨髄のSUV値を計測した。照射線量は治療計画3次元ＣＴ画像より求めた。治療線量の10％以上を照射野とし、照射線量の違いを10-30％と30％を超える部位で検討した。肋骨は全例で照射野に含まれ、脊椎(2例)、肩甲骨（7例）、胸骨(2例)も照射野に含まれた。治療線量の10％以上の骨髄の集積は、治療直後から低下し、3か月後で少し回復の傾向を示したが、1年以上後では3か月後と同等であった。10-30％と30％を超える部位の間には相違はなかった。照射野外の骨髄集積は変化なかった。放射線治療による骨髄抑制は認められなかった。骨髄のFLT集積は、重粒子治療　4.2-4.4GyE/1回以上の照射された部分で低下し1年以上継続した。骨髄の放射線高感受性が画像で示され、FLT検査は骨髄機能評価に使用可能と推測される。　　","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"第49回日本核医学会学術総会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"小泉, 満"}],"nameIdentifiers":[{"nameIdentifier":"629051","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"佐賀, 恒夫"}],"nameIdentifiers":[{"nameIdentifier":"629052","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"犬伏, 正幸"}],"nameIdentifiers":[{"nameIdentifier":"629053","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"吉川, 京燦"}],"nameIdentifiers":[{"nameIdentifier":"629054","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"馬場, 雅行"}],"nameIdentifiers":[{"nameIdentifier":"629055","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"小泉 満","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"629056","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"佐賀 恒夫","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"629057","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"犬伏 正幸","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"629058","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"吉川 京燦","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"629059","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"馬場 雅行","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"629060","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"重粒子線治療肺癌患者に於ける18F-fluoro-deoxy-L-thymidine （FLT）の骨髄集積の変化","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"重粒子線治療肺癌患者に於ける18F-fluoro-deoxy-L-thymidine （FLT）の骨髄集積の変化"}]},"item_type_id":"10005","owner":"1","path":["29"],"pubdate":{"attribute_name":"公開日","attribute_value":"2009-12-18"},"publish_date":"2009-12-18","publish_status":"0","recid":"63734","relation_version_is_last":true,"title":["重粒子線治療肺癌患者に於ける18F-fluoro-deoxy-L-thymidine （FLT）の骨髄集積の変化"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T21:19:35.077689+00:00"}