{"created":"2023-05-15T14:46:21.786042+00:00","id":63633,"links":{},"metadata":{"_buckets":{"deposit":"05a5856d-a986-475b-ac24-0df192df8fb0"},"_deposit":{"created_by":1,"id":"63633","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"63633"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00063633","sets":["10:29"]},"author_link":["628067","628066","628069","628065","628070","628068"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2009-10-03","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The recent success with small fish as an animal model of cancer has attracted cancer researchers'attention because of the capability of directly visualizing tumor cells in vivo. Here we report a unique medaka model, in which we are able to observe various cell behaviors of in vivo transplanted tumor cells such as cell proliferation and metastasis. We established medaka melanoma (MM) cells stably expressing green fluorescence protein (GFP) and transplanted them into non-irradiated and irradiated medaka. The tumor cells were grown at the injection sites \nin medaka, and the spatiotemporal changes were visualized under fluorescence stereoscopic microscope with a cellular level-resolution, even at a single cell level. Tumor dormancy and metastasis were also observed. Interestingly, in irradiated medaka, accelerated tumor growth and metastasis of the transplanted tumor cells were directly visualized. Our medaka model provides a new opportunity to visualize in vivo tumor cells\"as seen in a culture dish\"","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"第68回日本癌学会学術総会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"長谷川, 純崇"}],"nameIdentifiers":[{"nameIdentifier":"628065","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"古川, 高子"}],"nameIdentifiers":[{"nameIdentifier":"628066","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"佐賀, 恒夫"}],"nameIdentifiers":[{"nameIdentifier":"628067","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"長谷川 純崇","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"628068","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"古川 高子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"628069","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"佐賀 恒夫","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"628070","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"メダカモデル：生体内がん細胞動態の直接観察","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"メダカモデル：生体内がん細胞動態の直接観察"}]},"item_type_id":"10005","owner":"1","path":["29"],"pubdate":{"attribute_name":"公開日","attribute_value":"2009-10-07"},"publish_date":"2009-10-07","publish_status":"0","recid":"63633","relation_version_is_last":true,"title":["メダカモデル：生体内がん細胞動態の直接観察"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T21:20:45.584611+00:00"}