{"created":"2023-05-15T14:46:20.162123+00:00","id":63607,"links":{},"metadata":{"_buckets":{"deposit":"40a981e6-06db-4103-8409-87fffbba45e7"},"_deposit":{"created_by":1,"id":"63607","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"63607"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00063607","sets":["10:29"]},"author_link":["627739","627751","627752","627753","627756","627747","627745","627746","627741","627754","627744","627750","627755","627740","627749","627742","627743","627748","627757"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2008-04-06","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"高エネルギーＸ線と薬品送達システム(Drug Delivery System)とを組み\n合わせたＸ線DDSのための薬剤として、重金属元素を含有したDDS薬剤が注目されてい\nる。キャリアと呼ばれる高分子ミセルに含有された薬剤は徐々に放出されるが、細胞\nに取り込まれているかどうかを確認することは難しい。そこで、PIXE（Particle\nInduced X-ray Emissions Analysis）分析法と、白金性抗癌剤を含むDDS薬剤（シス\nプラチンミセル）を用いて、CHO（Chinese Hamster Ovary）細胞内の白金含有量を測\n定した。その結果、DDS薬剤の状態では、普通の薬剤に比べて、細胞への取込みが\n1/10程度と低いことを確認した。PIXEを用いたDDS薬剤の性能評価について発表す\nる。","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"第95回日本医学物理学会学術大会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"水野, 和恵"}],"nameIdentifiers":[{"nameIdentifier":"627739","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"遊佐, 訓孝"}],"nameIdentifiers":[{"nameIdentifier":"627740","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"濱野, 毅"}],"nameIdentifiers":[{"nameIdentifier":"627741","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"小西, 輝昭"}],"nameIdentifiers":[{"nameIdentifier":"627742","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"磯, 浩之"}],"nameIdentifiers":[{"nameIdentifier":"627743","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"石川, 剛弘"}],"nameIdentifiers":[{"nameIdentifier":"627744","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"加藤, 宝光"}],"nameIdentifiers":[{"nameIdentifier":"627745","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"今関, 等"}],"nameIdentifiers":[{"nameIdentifier":"627746","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"岡安, 隆一"}],"nameIdentifiers":[{"nameIdentifier":"627747","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"上坂, 充"}],"nameIdentifiers":[{"nameIdentifier":"627748","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"水野 和恵","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"627749","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"濱野 毅","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"627750","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"小西 輝昭","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"627751","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"磯 浩之","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"627752","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"石川 剛弘","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"627753","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"加藤 宝光","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"627754","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"今関 等","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"627755","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"岡安 隆一","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"627756","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"上坂 充","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"627757","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"治療型X線DDSのPIXE分析","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"治療型X線DDSのPIXE分析"}]},"item_type_id":"10005","owner":"1","path":["29"],"pubdate":{"attribute_name":"公開日","attribute_value":"2009-10-06"},"publish_date":"2009-10-06","publish_status":"0","recid":"63607","relation_version_is_last":true,"title":["治療型X線DDSのPIXE分析"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T21:21:03.120941+00:00"}