{"created":"2023-05-15T14:46:18.871955+00:00","id":63578,"links":{},"metadata":{"_buckets":{"deposit":"265701cc-4f77-4363-8df6-a49f754115f9"},"_deposit":{"created_by":1,"id":"63578","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"63578"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00063578","sets":["10:29"]},"author_link":["627489","627492","627490","627491","627494","627493"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2008-04-15","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"We studied the localization of\nphosphorylated H2AX (gamma-H2AX) in cultured human\nfibroblasts (NB1RGB) and EYFP-tagged rad51 in\nChinese hamster CHO cells after irradiation with\nheavy ion beams. Asynchronous cells were\nirradiated with X-rays, carbon ion beam (LET is\nabout 30 keV/um and 85 keV/um), Si ion beam (220\nkeV/um) and Fe ion beam (440 keV/um) at room\ntemperature. The amount of gamma-H2AX monitored by\nflow cytometry increased just after irradiation of each\nradiation and reached maximum around 30 min. It\nwas then decreased quickly for cells irradiated with\nX-rays but presented longer for Si or Fe beams.\nAverage amount of gamma-H2AX per cells at 30 min after\nirradiation increased with dose for all radiations\ntested and was similar between Si and Fe beams and\nwas bigger than X-rays. Under the confocal\nmicroscopy, foci of gamma-H2AX on cell nucleus was not\nvisible just after X-irradiation, but obvious after Fe\nion irradiation. Number of foci per nucleus was\nincreased with increasing dose at 30 min after\nirradiation similarly for all radiation tested. On the\nother hand, rad51 foci were not visible just after\nirradiation and observed about 1 h after irradiation\nand were visible up to 10 h after irradiation.","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"平成19年度放射線医学総合研究所重粒子線がん治療装置等共同利用研究成果発表会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"江口−笠井, 清美"}],"nameIdentifiers":[{"nameIdentifier":"627489","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"辻田, 瑛那"}],"nameIdentifiers":[{"nameIdentifier":"627490","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"森, 雅彦"}],"nameIdentifiers":[{"nameIdentifier":"627491","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"笠井 清美","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"627492","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"辻田 瑛那","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"627493","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"森 雅彦","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"627494","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"重粒子線誘発DNA 障害の特徴","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"重粒子線誘発DNA 障害の特徴"}]},"item_type_id":"10005","owner":"1","path":["29"],"pubdate":{"attribute_name":"公開日","attribute_value":"2009-10-01"},"publish_date":"2009-10-01","publish_status":"0","recid":"63578","relation_version_is_last":true,"title":["重粒子線誘発DNA 障害の特徴"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T21:21:22.788976+00:00"}