{"created":"2023-05-15T14:46:07.056174+00:00","id":62996,"links":{},"metadata":{"_buckets":{"deposit":"2173a3af-72b2-4ee8-b7e5-6870812a6059"},"_deposit":{"created_by":1,"id":"62996","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"62996"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00062996","sets":["10:29"]},"author_link":["622211","622205","622203","622212","622209","622208","622207","622202","622213","622204","622210","622206"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2009-03-17","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Purpose: Analysis of the results of hypofractionated conformal carbon ion radiotherapy (C-ion RT) for localized prostate cancer was performed, with regard to normal tissue morbidity, biochemical relapse-free rate (bNED), and patient survival. Methods and Materials: Five hundreds and forty-two prostate cancer patients who received C-ion RT established through two preceding dose-escalation studies were analyzed in regard to toxicity, survival, and bNED. Results: Concerning radiation morbidity, no grade 3 or higher toxicities were observed either in the rectum or genitourinary system (GU), and the incidences of grade 2 rectum and GU morbidity were only 2.3% and 4.8%, respectively. The incidence of late GU toxicity in patients treated with 16 fractions of C-ion RT was lower than that of 20 fractions. Overall bNED at 5 years was 88.9%, with only four local recurrences. bNED of 16 fractions of C-ion RT was comparable to that of 20 fractions. Gleason's score, T-stage, and initial PSA were significant prognostic factors for bNED, and T-stage was also a significant prognostic factor for overall survival rate. The duration of hormonal therapy also had an impact on biochemical control in high-risk patients, but it appeared possible to apply C-ion RT with short-course hormonal therapy to intermediate-risk patients. Conclusion: C-ion RT with the established dose fractionation regimen yielded satisfactory bNED with very few local recurrences, and with minimal morbidity. C-ion RT of 16 fractions could offer even lower incidence of GU toxicity than that of 20 fractions.","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"NIRS-ETOILE Joint Symposium 2009 on Carbon Ion Radiotherapy","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Tsuji, Hiroshi"}],"nameIdentifiers":[{"nameIdentifier":"622202","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Okada, Toru"}],"nameIdentifiers":[{"nameIdentifier":"622203","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sugahara, Shinji"}],"nameIdentifiers":[{"nameIdentifier":"622204","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Serizawa, Itsuko"}],"nameIdentifiers":[{"nameIdentifier":"622205","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kamada, Tadashi"}],"nameIdentifiers":[{"nameIdentifier":"622206","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tsujii, Hirohiko"}],"nameIdentifiers":[{"nameIdentifier":"622207","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"辻 比呂志","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"622208","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"岡田 徹","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"622209","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"菅原 信二","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"622210","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"芹澤 慈子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"622211","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鎌田 正","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"622212","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"辻井 博彦","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"622213","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"Prostate Cancer","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Prostate Cancer"}]},"item_type_id":"10005","owner":"1","path":["29"],"pubdate":{"attribute_name":"公開日","attribute_value":"2009-03-19"},"publish_date":"2009-03-19","publish_status":"0","recid":"62996","relation_version_is_last":true,"title":["Prostate Cancer"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T21:24:23.114362+00:00"}