{"created":"2023-05-15T14:46:03.502250+00:00","id":62917,"links":{},"metadata":{"_buckets":{"deposit":"bb588343-930e-4ad1-8079-73ef22f1c0a6"},"_deposit":{"created_by":1,"id":"62917","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"62917"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00062917","sets":["10:29"]},"author_link":["621520","621514","621524","621527","621531","621517","621515","621521","621519","621532","621526","621528","621533","621525","621518","621516","621529","621530","621522","621523"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2008-09-12","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"C型肝炎は、日本における肝臓病死の最大の原因であり、その排除は肝硬変や肝癌の予防となることから、インターフェロン（IFN）や各種抗ウイルス薬による治療効果を高めることが急務である。我々は微量金属の亜鉛がC型肝炎ウイルス（HCV）に対して一定の抗ウイルス効果を有する事を報告してきた。しかし、亜鉛のHCVに対する作用は十分解明されていない。今回我々はin　vitro　HCV産生細胞（HCV replicon）でmicroPIXEおよびその他の定量系を用いてHCVと亜鉛の関わり、そのメカニズムについて検討を行った。","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"第２５回PIXEシンポジウム","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"滝澤, 大地"}],"nameIdentifiers":[{"nameIdentifier":"621514","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"高木, 均"}],"nameIdentifiers":[{"nameIdentifier":"621515","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"蒔田, 千香子"}],"nameIdentifiers":[{"nameIdentifier":"621516","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"中島, 有香"}],"nameIdentifiers":[{"nameIdentifier":"621517","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"斉藤, 悦子"}],"nameIdentifiers":[{"nameIdentifier":"621518","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"大山, 達也"}],"nameIdentifiers":[{"nameIdentifier":"621519","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"市川, 武"}],"nameIdentifiers":[{"nameIdentifier":"621520","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"柿崎, 暁"}],"nameIdentifiers":[{"nameIdentifier":"621521","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"佐藤, 賢"}],"nameIdentifiers":[{"nameIdentifier":"621522","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"森, 昌朋"}],"nameIdentifiers":[{"nameIdentifier":"621523","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"勝矢, 陽子"}],"nameIdentifiers":[{"nameIdentifier":"621524","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"小山, 洋"}],"nameIdentifiers":[{"nameIdentifier":"621525","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"草壁, 孝彦"}],"nameIdentifiers":[{"nameIdentifier":"621526","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"中里, 享美"}],"nameIdentifiers":[{"nameIdentifier":"621527","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"長嶺, 竹明"}],"nameIdentifiers":[{"nameIdentifier":"621528","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"佐藤, 隆博"}],"nameIdentifiers":[{"nameIdentifier":"621529","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"及川, 将一"}],"nameIdentifiers":[{"nameIdentifier":"621530","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"神谷, 富裕"}],"nameIdentifiers":[{"nameIdentifier":"621531","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"荒川, 和夫"}],"nameIdentifiers":[{"nameIdentifier":"621532","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"酒井, 卓郎"}],"nameIdentifiers":[{"nameIdentifier":"621533","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"HCV　repliconにおける亜鉛動態","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"HCV　repliconにおける亜鉛動態"}]},"item_type_id":"10005","owner":"1","path":["29"],"pubdate":{"attribute_name":"公開日","attribute_value":"2008-12-15"},"publish_date":"2008-12-15","publish_status":"0","recid":"62917","relation_version_is_last":true,"title":["HCV　repliconにおける亜鉛動態"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T21:25:15.460664+00:00"}