{"created":"2023-05-15T14:45:57.815732+00:00","id":62790,"links":{},"metadata":{"_buckets":{"deposit":"fe251e19-007a-41e7-a253-5aacb8b3f646"},"_deposit":{"created_by":1,"id":"62790","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"62790"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00062790","sets":["10:29"]},"author_link":["620145","620157","620150","620147","620158","620143","620148","620154","620144","620153","620155","620146","620156","620142","620149","620151","620141","620152"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2008-10-18","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"【目的】肝細胞癌の多くは慢性肝疾患を背景に有し切除不能な症例が少なくない。経皮的局所治療は小さな腫瘍には有効だが大きな腫瘍では再発が多く、肝動脈化学塞栓療法も治療効果が不完全であることが多い。今回、主に他治療では十分な効果を望めないか他治療が無効であった大きな肝細胞癌に対する炭素イオン線治療の効果と有害反応を検証した。\n【対象と方法】対象は1996年1月から2007年2月に炭素イオン線治療が施行された径7ｃｍ以上の肝細胞癌18例、観察期間の中央値は30か月（10-87か月）、Child-Pugh分類による肝障害度はA15例、B3例、腫瘍径は7-12cmであった。照射法は、15回/5週（60.0-72.0GyE)4例、12回/3週（60.0GyE)1例、8回/2週（52.8,58.0GyE)2例、4回/1週（52.8GyE)6例、2回/2日（38.8GyE)5例であった。生存、局所制御、肝有害反応を評価した。\n【結果】1年、3年、5年生存率はそれぞれ78％、52％、22％であった。局所再発は4例にみられ、うち2例は線量増加試験で線量が低い症例（60.0GyE/15回、52.8GyE/8回）であった。肝機能が評価できた13例の照射後3-12か月のChild-Pugh scoreの変化は0、1が12例、2が1例であった。\n【結語】炭素イオン線治療は大きな肝細胞癌に対しても十分な線量を投与すれば高い局所効果が望め、安全に行える治療であると考えられた。","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"日本放射線腫瘍学会第21回学術大会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"安田, 茂雄"}],"nameIdentifiers":[{"nameIdentifier":"620141","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"加藤, 博敏"}],"nameIdentifiers":[{"nameIdentifier":"620142","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"柳, 剛"}],"nameIdentifiers":[{"nameIdentifier":"620143","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"今田, 浩史"}],"nameIdentifiers":[{"nameIdentifier":"620144","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"山田, 滋"}],"nameIdentifiers":[{"nameIdentifier":"620145","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"原, 竜介"}],"nameIdentifiers":[{"nameIdentifier":"620146","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鎌田, 正"}],"nameIdentifiers":[{"nameIdentifier":"620147","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"溝江, 純悦"}],"nameIdentifiers":[{"nameIdentifier":"620148","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"辻井, 博彦"}],"nameIdentifiers":[{"nameIdentifier":"620149","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"安田 茂雄","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"620150","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"加藤 博敏","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"620151","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"柳 剛","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"620152","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"今田 浩史","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"620153","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"山田 滋","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"620154","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"原 竜介","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"620155","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鎌田 正","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"620156","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"溝江 純悦","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"620157","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"辻井 博彦","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"620158","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"大きな肝細胞癌に対する炭素イオン線治療","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"大きな肝細胞癌に対する炭素イオン線治療"}]},"item_type_id":"10005","owner":"1","path":["29"],"pubdate":{"attribute_name":"公開日","attribute_value":"2008-10-21"},"publish_date":"2008-10-21","publish_status":"0","recid":"62790","relation_version_is_last":true,"title":["大きな肝細胞癌に対する炭素イオン線治療"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T21:26:44.391205+00:00"}