@misc{oai:repo.qst.go.jp:00062689, author = {Hirayama, Ryoichi and Furusawa, Yoshiya and Murayama, Chieko and Kusano, Yohsuke and Ito, Atsushi and 平山 亮一 and 古澤 佳也 and 村山 千恵子 and 伊藤 敦}, month = {Sep}, note = {To evaluate the contribution of indirect action mediated by OH radicals in biological effects of high LET radiations, we examined the production of 8-hydroxy-2-deoxyguanosine (8-OHdG) in 2-deoxyguanosine aqueous solution using various ion species with an LET range from 20 to 300 keV/mm. The 8-OHdG yield decreased with increasing LET. In the hypoxic irradiation condition, the yield showed constant or rather increasing tendency above about 100 keV/mm, which is consistent with an oxygen-in-the-track hypothesis to explain the diminishment of oxygen effect., The 2nd Asia-Pacific Symposium on Radiation Chemistry (APSRC-2008)}, title = {LET dependence of oxidative DNA base damage in 2-deoxyguanine aqueous solution irradiated with heavy ions}, year = {2008} }