{"created":"2023-05-15T14:45:52.905941+00:00","id":62681,"links":{},"metadata":{"_buckets":{"deposit":"d67286d6-bd6f-4fb5-8e9c-936e65d74e50"},"_deposit":{"created_by":1,"id":"62681","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"62681"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00062681","sets":["10:29"]},"author_link":["619181","619177","619178","619175","619183","619179","619185","619182","619184","619180","619176","619174"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2008-04-15","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"To identify molecular mechanism of effectiveness induced by carbon-ion radiotherapy, we investigated expression profiles of murine tumors, which varied its radiosensitivity to gamma irradiation, using microarrays consisting of 55K genes. Six murine tumors (squamous cell carcinoma: NR-S1, SCCVII, Fibrosarcoma: NFSa, #8520, and Mammary carcinoma: MCa#4, MMCa) were transplanted in hind legs of C3H/Henirs mice and solid tumors were irradiated with either carbon-ion beam or gamma-ray. In microarray analysis, the pairwise comparisons between pre-treatment sample and post- treatment\n sample at 6h, 1 day, and 3 day after irradiation in each tumor were made by Wilcoxon test.\n We detected several tens of genes, whose expressions were significantly changed after carbon-irradiation. These genes were ontologically categorized into cell-cycle and immune response. Furthermore, comparison of expression intensity between radiosensitive (SCC-VII) and radioresistant (NR- S1) tumors by ANOVA test revealed a candidate molecule to be related with radioresistance.","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"H19年度HIMAC共同利用研究成果発表会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"岩川, 眞由美"}],"nameIdentifiers":[{"nameIdentifier":"619174","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"野尻, 和典"}],"nameIdentifiers":[{"nameIdentifier":"619175","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"田巻, 倫明"}],"nameIdentifiers":[{"nameIdentifier":"619176","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"酒井, 美奈子"}],"nameIdentifiers":[{"nameIdentifier":"619177","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"今留, 香織"}],"nameIdentifiers":[{"nameIdentifier":"619178","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"今井, 高志"}],"nameIdentifiers":[{"nameIdentifier":"619179","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"岩川 眞由美","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"619180","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"野尻 和典","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"619181","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"田巻 倫明","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"619182","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"酒井 美奈子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"619183","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"今留 香織","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"619184","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"今井 高志","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"619185","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"マウス腫瘍の重粒子線照射効果関連遺伝子群の網羅的解析","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"マウス腫瘍の重粒子線照射効果関連遺伝子群の網羅的解析"}]},"item_type_id":"10005","owner":"1","path":["29"],"pubdate":{"attribute_name":"公開日","attribute_value":"2008-08-19"},"publish_date":"2008-08-19","publish_status":"0","recid":"62681","relation_version_is_last":true,"title":["マウス腫瘍の重粒子線照射効果関連遺伝子群の網羅的解析"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T21:27:59.910460+00:00"}