{"created":"2023-05-15T14:45:51.879433+00:00","id":62658,"links":{},"metadata":{"_buckets":{"deposit":"2604ea23-1367-4dcf-a268-d268a08c782e"},"_deposit":{"created_by":1,"id":"62658","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"62658"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00062658","sets":["10:29"]},"author_link":["619014","619012","619016","619011","619018","619017","619019","619020","619010","619015","619013"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2008-05-30","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Nanohybrids for Multimodal Molecular Imaging: Synthesis, Spectral Characteristics and Application\nAuthors : Z. Zhelev, R. Bakalova, I. Aoki, K. Yoneyama, M. Obata, V. Gadjeva,* I. Kanno Molecular\nImaging Center, National Institute of Radiological Sciences, NIRS, 4-9-1 Anagawa, Inage, Chiba\n263-8555, Japan *Department of Chemistry and Biochemistry, Thracian University, Stara Zagora,\nResume : The architecture of biocompatible nanoparticles allows a development of novel molecular\nprobes with multimodality for simultaneous application in different imaging techniques, e.g., optical\nimaging, magnetic resonance imaging (MRI), positron emission tomography (PET), X-ray, electron\nparamagnetic resonance (EPR) imaging, etc. These probes open new trends in development of\nmultimodal imaging instruments – the future of bioimaging. The present study describes a synthesis\nof several original nanohybrids for multimodal imaging. They are based on organic/inorganic-coated\nmetal nanoparticles, dendrimers, ion chelators, paramagnetic fatty acids, and spin-labeled\nnitrosoureas and triazenes. The probes are functionalized with different ligands attached on their\nsurface or incorporated into the structure. The nanohybrids are divided in two groups according to\ntheir spectral characteristics. The probes from the first group are characterized with strong\nphotoluminescence and MRI contrast signals and could be applied simultaneously in fluorescent\nimaging and MRI. The probes from the second group are characterized with strong MRI and EPR\nsignals and could be applied simultaneously in MRI and EPR imaging. The structure of some\nnanoparticles allows an approximate calculation of their concentration in moles, which is beneficial\nfor dose-dependent analyses in the life science. All materials were tested for biocompatibility and\napplied in the imaging of molecular targets on cells and animals.","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"Ethe 15th International Symposium on Nanoscience and Nanotechnology E-MRS 2008Spring Meeting","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Zhelev, Zhivko"}],"nameIdentifiers":[{"nameIdentifier":"619010","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Bakalova-Zheleva, Rumiana"}],"nameIdentifiers":[{"nameIdentifier":"619011","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Aoki, Ichio"}],"nameIdentifiers":[{"nameIdentifier":"619012","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Obata, Takayuki"}],"nameIdentifiers":[{"nameIdentifier":"619013","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kanno, Iwao"}],"nameIdentifiers":[{"nameIdentifier":"619014","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"et.al"}],"nameIdentifiers":[{"nameIdentifier":"619015","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ｚｈｅｌｅｖ Ｚｈｉｖｋｏ","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"619016","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"バカロバ ルミアナ","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"619017","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"青木 伊知男","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"619018","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"小畠 隆行","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"619019","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"菅野 巖","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"619020","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"Nanohybrids for Multimodal Molecular imaging: Synthesis, Spectral Characteristics and Applications","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Nanohybrids for Multimodal Molecular imaging: Synthesis, Spectral Characteristics and Applications"}]},"item_type_id":"10005","owner":"1","path":["29"],"pubdate":{"attribute_name":"公開日","attribute_value":"2008-08-04"},"publish_date":"2008-08-04","publish_status":"0","recid":"62658","relation_version_is_last":true,"title":["Nanohybrids for Multimodal Molecular imaging: Synthesis, Spectral Characteristics and Applications"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T21:28:15.321406+00:00"}