@misc{oai:repo.qst.go.jp:00062483,
 author = {Sugane, Toshio and Baba, Masayuki and Yamamoto, Naoyoshi and Nakajima, Mio and Miyamoto, Tadaaki and Mori, Shinichiro and Minohara, Shinichi and Kandatsu, Susumu and Kamada, Tadashi and Mizoe, Junetsu and Tsujii, Hirohiko and 須金 紀雄 and 馬場 雅行 and 山本 直敬 and 中嶋 美緒 and 宮本 忠昭 and 森 慎一郎 and 蓑原 伸一 and 神立 進 and 鎌田 正 and 溝江 純悦 and 辻井 博彦},
 month = {Mar},
 note = {Purpose: High control rates and minimal adverse reactions were reported in National Institute of Radiological Sciences, Chiba, Japan for the stage I non-small cell lung cancer (NSCLC) with carbon ion radiotherapy (CIRT).
We describe our current planning methods in CIRT for the patients with NSCLC located in the peripheral or hilar regions. 
Methods: The NSCLC on the peripheral zone of the lung was treated from 4-portal oblique irradiation directions with single fractionation. In contrast, the central type of the NSCLC was irradiated with total dose 68.4GyE in 12 fractions. We define the two targets such as CTV-1 included the bronchus near the tumor and CTV-2 excluded the bronchus near the tumor as much as possible. We irradiated CTV-1 and CTV-2 with total dose 51.3GyE/9 fractions and total dose 17.1GyE/3fractions each other. All of patients treated with these planning were enrolled to the clinical trials.
Results: We did not experience severe adverse reaction to date in these protocol studies. We estimate the significant effect of these treatments from conventional progress. We reveal the relation between PTV and the respiratory movement of the tumor by the four-dimensional CT (4D-CT) under free breathing in several cases of the peripheral type. We compare the findings by the periodic bronchosopy with dose distribution on the inside of the bronchus by the virtual bronchoscopy in the hilar lung cancer.
Conclusions: We performed the each different treatment planning of patients with the NSCLC. We have to treat more patients to demonstrate the effectiveness and impact of these planning by the 4DCT or by the dose distribution on the virtual bronchoscopy., NIRS-MD Anderson Symposium on Clinical Issues for Particle Therapy},
 title = {Treatment Planning in Carbon Ion Radiotherapy for Lung Cancer},
 year = {2008}
}