{"created":"2023-05-15T14:45:41.002714+00:00","id":62418,"links":{},"metadata":{"_buckets":{"deposit":"1a04aa7b-974e-4ff6-a74e-bb585e7fc987"},"_deposit":{"created_by":1,"id":"62418","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"62418"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00062418","sets":["10:29"]},"author_link":["616869","616866","616870","616867","616868","616871","616877","616872","616876","616878","616873","616875","616879","616874","616865"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2007-05-18","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"アルツハイマー病(AD)における脳内アミロイド沈着部位を明らかにする.【対象/方法】AD13例(年齢70±8歳,M:F=4:9,MMSE18±5),MCI9例(年齢75±4歳,M:F=7:2,MMSE28±2),健常対照17例(年齢67±11歳,M:F=7:10,MMSE28±2).[11C]-PIBを静注後90分間脳内放射能を測定し,血漿入力関数を用いてLogan plot解析して分布容積比を算出し,脳内アミロイド結合の指標とした.SPM2を用いて健常群とAD群,健常群とMCI群とのt検定を行った.【結果】AD群では頭頂連合野,帯状回,前頭連合野,外側側頭葉等において有意なアミロイド沈着を認めた(p＜0.01,ET＞69).MCI群では9例中6例でADと同様なアミロイド沈着が認めた.【結論】ADにおける脳内アミロイド沈着部位がPETで示された.","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"第48回日本神経学会総会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"島田, 斉"}],"nameIdentifiers":[{"nameIdentifier":"616865","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"篠遠, 仁"}],"nameIdentifiers":[{"nameIdentifier":"616866","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"佐藤, 康一"}],"nameIdentifiers":[{"nameIdentifier":"616867","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"田中, 典子"}],"nameIdentifiers":[{"nameIdentifier":"616868","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"黄田, 常嘉"}],"nameIdentifiers":[{"nameIdentifier":"616869","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"須原, 哲也"}],"nameIdentifiers":[{"nameIdentifier":"616870","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"入江, 俊章"}],"nameIdentifiers":[{"nameIdentifier":"616871","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"その他"}],"nameIdentifiers":[{"nameIdentifier":"616872","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"島田 斉","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"616873","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"篠遠 仁","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"616874","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"佐藤 康一","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"616875","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"田中 典子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"616876","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"黄田 常嘉","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"616877","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"須原 哲也","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"616878","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"入江 俊章","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"616879","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"[11C]-PIB PETによるアルツハイマー病の脳内アミロイドイメージング","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"[11C]-PIB PETによるアルツハイマー病の脳内アミロイドイメージング"}]},"item_type_id":"10005","owner":"1","path":["29"],"pubdate":{"attribute_name":"公開日","attribute_value":"2008-01-30"},"publish_date":"2008-01-30","publish_status":"0","recid":"62418","relation_version_is_last":true,"title":["[11C]-PIB PETによるアルツハイマー病の脳内アミロイドイメージング"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T21:31:00.608202+00:00"}