{"created":"2023-05-15T14:45:17.401595+00:00","id":61889,"links":{},"metadata":{"_buckets":{"deposit":"a1424459-611f-4a02-bc81-8477bfa74406"},"_deposit":{"created_by":1,"id":"61889","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"61889"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00061889","sets":["10:29"]},"author_link":["612438","612441","612450","612448","612439","612445","612447","612453","612443","612449","612451","612446","612444","612442","612440","612452"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2006-11-11","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"活性化ミクログリアに発現する末梢性ベンゾジアゼピンレセプターのリガンドである[F-18] FEDAA1106の脳内動態は、2-tissueCompartment Modelで再現でき、Nonlinear-Least Square(NLS)法によりBinding Potential(BP)値が算出される。しかし、時間放射能曲線のS/Nが低い場合には推定されたBP値にバイアスが生じることが知られており、BPの画像化における問題点となっている。本研究では、健常志願者7名の[F-18] FEDAA1106-PETデータを用い、ガウス、Wavelet両フィルターを再構成画像に施した場合のBP画像の比較を行った。フィルターをかけないBP画像では、約10％のバイアスが確認された。また、ガウスフィルターを施したBP画像に比べ、Waveletフィルターを施したBP画像は、空間分解能を損なうことなくバイアスの改善を示した。","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"第46回日本核医学会学術総会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"志田原, 美保"}],"nameIdentifiers":[{"nameIdentifier":"612438","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"藤村, 洋太"}],"nameIdentifiers":[{"nameIdentifier":"612439","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"生駒, 洋子"}],"nameIdentifiers":[{"nameIdentifier":"612440","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"関, 千江"}],"nameIdentifiers":[{"nameIdentifier":"612441","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"伊藤, 浩"}],"nameIdentifiers":[{"nameIdentifier":"612442","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鈴木, 和年"}],"nameIdentifiers":[{"nameIdentifier":"612443","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"菅野, 巖"}],"nameIdentifiers":[{"nameIdentifier":"612444","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"須原, 哲也"}],"nameIdentifiers":[{"nameIdentifier":"612445","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"志田原 美保","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"612446","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"藤村 洋太","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"612447","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"生駒 洋子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"612448","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"関 千江","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"612449","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"伊藤 浩","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"612450","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鈴木 和年","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"612451","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"菅野 巖","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"612452","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"須原 哲也","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"612453","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"[F-18]FEDAA1106によるレセプター結合能のパラメトリック画像計算の検討","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"[F-18]FEDAA1106によるレセプター結合能のパラメトリック画像計算の検討"}]},"item_type_id":"10005","owner":"1","path":["29"],"pubdate":{"attribute_name":"公開日","attribute_value":"2006-11-13"},"publish_date":"2006-11-13","publish_status":"0","recid":"61889","relation_version_is_last":true,"title":["[F-18]FEDAA1106によるレセプター結合能のパラメトリック画像計算の検討"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T21:37:06.739174+00:00"}