@misc{oai:repo.qst.go.jp:00061844,
 author = {Yamada, Shigeru and Kamada, Tadashi and Hara, Ryusuke and Katou, Hirotoshi and Yasuda, Shigeo and Kano, Masayuki and Kato, Shingo and Ohno, Tatsuya and Imai, Reiko and Tsujii, Hirohiko and 山田 滋 and 鎌田 正 and 原 竜介 and 加藤 博敏 and 安田 茂雄 and 加野 将之 and 加藤 眞吾 and 大野 達也 and 今井 礼子 and 辻井 博彦},
 month = {Oct},
 note = {ABSTRACTS: BACKGROUND: Carbon ion radiotherapy is effective and safe in the management of patients with pelvic tumors. Intestines are critical organs for this treatment. To exclude the small intestine and colon from the clinical target volume (CTV) and reduce the exposure of them, we use expanded polytetrafluoroethylene (Gore-Tex soft-tissue patch, W. L. Gore & Assoc Inc, Flagstaff, Ariz) which is a strong and easy-to-use material and dose not need to be removed after the conclusion of radiotherapy.
\nMETHODS: Between December 2004 and February 2006, Gore-Tex soft-tissue patches were used in 13 patients: 8 recurrent rectal cancers, 1 recurrent colon cancer, 2 pelvic sarcomas and 2 ovarian cancers. Eight tumors originated in the pelvic side wall, 3 in the presacral region and 2 in the colorectal anastomosis. Gore-Tex soft-tissue patches are placed between pelvic tumors and intestines. The total dose ranged from 52.8 to 73.6 gray equivalent (GyE) .
\nRESULTS: The tolerance of the intestines to radiation therapy has been satisfactory in each case, with a mean follow-up of 7.2 months (range 2 to 20).  All patients underwent carbon ion radiotherapy after a mean delay of 14.5 days (range 10-39) and 11 patients (85%) could enter carbon ion radiotherapy within 14 days. Two patients had adhesive ileuses after operation, and they were given the conservative treatments. All patients completed the scheduled treatment course. No grade 3 and 5 acute toxicity was observed. There were relatively few and mild toxicities in these patients. The overall local control rates at one year were 100%All patients are surviving.
\nCONCLUSIONS: Gore-Tex is a safe and effective implant material to prevent intestinal damages from carbon ion radiation in successful treatment of pelvic tumors., Particle Therapy Co-Operative Group PTCOG 45},
 title = {The protection of the small intestine and colon from carbon ion particle irradiation by means of Gore-Tex soft tissue patches  for patients with pelvic tumors            for patients with pelvic tumors},
 year = {2006}
}