{"created":"2023-05-15T14:45:03.851808+00:00","id":61584,"links":{},"metadata":{"_buckets":{"deposit":"83ad2b75-1f24-4e1c-b4e6-6f8368706bf4"},"_deposit":{"created_by":1,"id":"61584","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"61584"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00061584","sets":["10:29"]},"author_link":["609461","609464","609465","609466","609468","609459","609472","609456","609455","609462","609454","609471","609460","609467","609469","609470","609457","609463","609458"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2004-11-06","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"〔11Ｃ〕MP4P/PETにより、特に大脳皮質や眼床などの低〜中等度AChE活性領域において信頼性の高いｋ３値（AChE活性の指標）が得られている。標準解析法は、静脈採血により得られた人力関数を用い、対象領域の時間放射能推移を非線型最小二乗法で解析する方法である。今回は、類似トレーサーの〔11C〕MP4Aで報告された間便法（活性の十分高い領域への放射能集積が、人力関数の時間積分に比例すると仮定する参照法）を、健常13例で検討した。線条体を参照領域とし、（1）線形解析法、（2）非線形解析法、（3）対象領域と参照領域の放射能濃度比の時間推移を指数関数で近似して解析するHerholz法で解析した。大脳皮質や視床のｋ3値は、標準法に対し、（1）（2）法ではプラス、（3）法ではマイナスのバイアスをもつ傾向が認められたが、変動係数（SD/mean）は、標準法と同程度であり、これらの参照法の有用性が示唆された。","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"第44回日本核医学会総会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"佐藤, 康一"}],"nameIdentifiers":[{"nameIdentifier":"609454","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"福士, 清"}],"nameIdentifiers":[{"nameIdentifier":"609455","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"篠遠, 仁"}],"nameIdentifiers":[{"nameIdentifier":"609456","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"田中, 典子"}],"nameIdentifiers":[{"nameIdentifier":"609457","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"黄田, 常嘉"}],"nameIdentifiers":[{"nameIdentifier":"609458","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"白石, 哲也"}],"nameIdentifiers":[{"nameIdentifier":"609459","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"平野, 成樹"}],"nameIdentifiers":[{"nameIdentifier":"609460","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"棚田, 修二"}],"nameIdentifiers":[{"nameIdentifier":"609461","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"伊豫, 雅臣"}],"nameIdentifiers":[{"nameIdentifier":"609462","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"入江, 俊章"}],"nameIdentifiers":[{"nameIdentifier":"609463","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"佐藤 康一","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"609464","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"福士 清","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"609465","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"篠遠 仁","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"609466","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"田中 典子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"609467","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"黄田 常嘉","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"609468","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"白石 哲也","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"609469","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"平野 成樹","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"609470","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"棚田 修二","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"609471","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"入江 俊章","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"609472","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"〔11C〕MP4P/PETを用いた脳内ACｈE活性測定における内部標準参照解析法の検討","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"〔11C〕MP4P/PETを用いた脳内ACｈE活性測定における内部標準参照解析法の検討"}]},"item_type_id":"10005","owner":"1","path":["29"],"pubdate":{"attribute_name":"公開日","attribute_value":"2006-07-04"},"publish_date":"2006-07-04","publish_status":"0","recid":"61584","relation_version_is_last":true,"title":["〔11C〕MP4P/PETを用いた脳内ACｈE活性測定における内部標準参照解析法の検討"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T21:40:41.949316+00:00"}