{"created":"2023-05-15T14:44:59.709606+00:00","id":61492,"links":{},"metadata":{"_buckets":{"deposit":"00d5ab1a-21d9-4424-a666-eb5411b7c7a9"},"_deposit":{"created_by":1,"id":"61492","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"61492"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00061492","sets":["10:29"]},"author_link":["608454","608445","608448","608453","608444","608451","608452","608441","608446","608449","608440","608447","608450","608443","608442"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2005-06-28","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The generator nuclide 62Cu (T1/2 = 9.7 min) is a suitable positron emitter for repeated PET study without a cyclotron. A 62Zn/62Cu generator, which employs an anion exchange resin as a generator column [1], has been widely used as a 62Cu source for the synthesis of useful 62Cu-labeled radiopharmaceuticals, such as 62Cu-PTSM [2, 3]. However, this generator had some disadvantages such as high osmotic pressure, low pH and low elution efficiency. Another type of 62Zn/62Cu generator, which uses a strong cation exchange resin as a generator column and glycine (Gly) solution for the elution of 62Cu, has been developed by Fujibayashi et al. [4]. This generator yields 62Cu solutions with high elution efficiency under physiological conditions. However, the 62Cu solution was contaminated by relatively large amount of 62Zn (~2.2%).  We found that the 62Cu elution efficiency and 62Zn leakage level were highly improved using the Sep Pak CM cartridge, which is a silica based weak anion exchanger.  Therefore, we applied this cartridge to the 62Zn/62Cu generator to establish a generator column. We report here the improved 62Zn/62Cu generator and its performance.","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"16th　International Symposium on Radiopharmaceutical Chemistry","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Fukumura, Toshimitsu"}],"nameIdentifiers":[{"nameIdentifier":"608440","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Okada, Kazuhiro"}],"nameIdentifiers":[{"nameIdentifier":"608441","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nakao, Ryuji"}],"nameIdentifiers":[{"nameIdentifier":"608442","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Suzuki, Hisashi"}],"nameIdentifiers":[{"nameIdentifier":"608443","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Mukai, Kensaku"}],"nameIdentifiers":[{"nameIdentifier":"608444","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ferenc, Szelecsenyi"}],"nameIdentifiers":[{"nameIdentifier":"608445","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kovacs, Zoltan"}],"nameIdentifiers":[{"nameIdentifier":"608446","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Suzuki, Kazutoshi"}],"nameIdentifiers":[{"nameIdentifier":"608447","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"福村 利光","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"608448","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"中尾 隆士","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"608449","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鈴木 寿","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"608450","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"向井 健作","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"608451","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ｆｅｒｅｎｃ Ｓｚｅｌｅｃｓｅｎｙｉ","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"608452","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"ゾルタン コバックス","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"608453","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鈴木 和年","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"608454","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"Improvement of 62Zn/62Cu generator based on cation exchange methods and its quality control.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Improvement of 62Zn/62Cu generator based on cation exchange methods and its quality control."}]},"item_type_id":"10005","owner":"1","path":["29"],"pubdate":{"attribute_name":"公開日","attribute_value":"2006-06-15"},"publish_date":"2006-06-15","publish_status":"0","recid":"61492","relation_version_is_last":true,"title":["Improvement of 62Zn/62Cu generator based on cation exchange methods and its quality control."],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T21:41:47.873367+00:00"}