{"created":"2023-05-15T14:44:52.124207+00:00","id":61328,"links":{},"metadata":{"_buckets":{"deposit":"e0029d14-ef25-41ab-b757-0dbede6cae44"},"_deposit":{"created_by":1,"id":"61328","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"61328"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00061328","sets":["10:29"]},"author_link":["606942","606943","606950","606948","606944","606947","606940","606945","606941","606949","606946"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2006-03-30","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"がんの放射線治療において、深部標的腫瘍に対する照射に伴い周辺正常組織の障害が発現することがある。放射線治療に伴う副作用として、深部がん照射における腸管の穿孔や皮膚障害などが挙げられるが、これらの副作用の発現は、患者の治療線量や照射領域を決定する治療計画の制限要因となっている。正常組織障害は色々な方法で定量評価されているが、早期反応にとって重要な細胞増殖（repopulation）を評価する方法は限られている。また我々は、これらの放射線障害に対する防護薬剤の研究も実施しており、各薬剤の防護作用を早期に定量評価することも主要な課題の一つとなっている。今回我々は14C-thymidineをトレーサーとして用いることで、主要な副作用発現部位である腸管障害の定量および薬剤の放射線防護効果の評価をDNA合成能の観点からin vivoにて試みた。","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"日本薬学会第126年会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"渡邉, 雅彦"}],"nameIdentifiers":[{"nameIdentifier":"606940","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"高井, 伸彦"}],"nameIdentifiers":[{"nameIdentifier":"606941","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"安藤, 興一"}],"nameIdentifiers":[{"nameIdentifier":"606942","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鵜澤, 玲子"}],"nameIdentifiers":[{"nameIdentifier":"606943","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"扶川, 武志"}],"nameIdentifiers":[{"nameIdentifier":"606944","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"その他"}],"nameIdentifiers":[{"nameIdentifier":"606945","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"渡邉 雅彦","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"606946","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"高井 伸彦","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"606947","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"安藤 興一","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"606948","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鵜澤 玲子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"606949","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"扶川 武志","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"606950","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"[2-14C]thymidineによる腸管放射線障害および薬剤防護効果の定量評価","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"[2-14C]thymidineによる腸管放射線障害および薬剤防護効果の定量評価"}]},"item_type_id":"10005","owner":"1","path":["29"],"pubdate":{"attribute_name":"公開日","attribute_value":"2006-04-05"},"publish_date":"2006-04-05","publish_status":"0","recid":"61328","relation_version_is_last":true,"title":["[2-14C]thymidineによる腸管放射線障害および薬剤防護効果の定量評価"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T21:43:39.787535+00:00"}