{"created":"2023-05-15T14:44:16.189212+00:00","id":60530,"links":{},"metadata":{"_buckets":{"deposit":"2241a13f-667e-4bff-84f3-67ff7ff258ff"},"_deposit":{"created_by":1,"id":"60530","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"60530"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00060530","sets":["10:29"]},"author_link":["600672","600662","600659","600667","600668","600669","600661","600670","600658","600671","600663","600664","600665","600657","600666","600673","600660"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2004-04-10","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Purpose: To investigate the biological effects of combining carbon-beam and X-ray in vitro. Methods and Materials: Cultured cells from human salivary gland cancer (HSGc-C5 cells) were irradiatied with a single source of carbon-beam (320 MeV/nucleon) or X-ray (4 MV), or with a combination of the two. Cell survivals were evaluated by clonogenic assay and survival curves were fitted using the LQ model. Sensitivity with long interval (72 hours) irradiation was also assessed. Theoretical survival curve of the combination was proposed with estimation of the cytotoxicity using actual carbon-beam and X-ray curves. Results: Carbon-beam showed the strongest effect, X-ray the weakest, and the combination intermediate for physical doses. The sequence of combination of carbon-beam and X-ray did not affect clonogenic survival. For biological equivalent doses, carbon-beam, X-ray, and the combination of both had equal effects. The theoretical survival curves corresponded well to the actual curves of the combination. The same results were observed with long interval irradiation. Conclusions: The biological effects of combining carbon-beam and X-ray were additive but not synergistic in vitro. These results may provide important and novel information about the combination of carbon-beam and X-ray irradiation.","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"第63回日本医学放射線学会学術発表会","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"出水, 祐介"}],"nameIdentifiers":[{"nameIdentifier":"600657","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"香川, 一史"}],"nameIdentifiers":[{"nameIdentifier":"600658","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"江島, 泰生"}],"nameIdentifiers":[{"nameIdentifier":"600659","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"西村, 英輝"}],"nameIdentifiers":[{"nameIdentifier":"600660","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"佐々木, 良平"}],"nameIdentifiers":[{"nameIdentifier":"600661","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"副島, 俊典"}],"nameIdentifiers":[{"nameIdentifier":"600662","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"古澤, 佳也"}],"nameIdentifiers":[{"nameIdentifier":"600663","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"菱川, 良夫"}],"nameIdentifiers":[{"nameIdentifier":"600664","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"杉村, 和朗"}],"nameIdentifiers":[{"nameIdentifier":"600665","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"出水 祐介","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"600666","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"香川 一史","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"600667","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"江島 泰生","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"600668","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"西村 英輝","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"600669","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"佐々木 良平","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"600670","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"古澤 佳也","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"600671","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"菱川 良夫","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"600672","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"杉村 和朗","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"600673","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"Combination of carbon-beam and X-ray: biologically synergistic or additive?","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Combination of carbon-beam and X-ray: biologically synergistic or additive?"}]},"item_type_id":"10005","owner":"1","path":["29"],"pubdate":{"attribute_name":"公開日","attribute_value":"2004-09-08"},"publish_date":"2004-09-08","publish_status":"0","recid":"60530","relation_version_is_last":true,"title":["Combination of carbon-beam and X-ray: biologically synergistic or additive?"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T21:52:44.336704+00:00"}