@misc{oai:repo.qst.go.jp:00060123, author = {Imaseki, Hitoshi and Ishikawa, Takahiro and Iso, Hiroyuki and Hamano, Tsuyoshi and Matsumoto, Kenichi and Yasuda, Nakahiro and Yukawa, Masae and 今関 等 and 石川 剛弘 and 濱野 毅 and 松本 健一 and 安田 仲宏 and 湯川 雅枝}, month = {Nov}, note = {National Institute of Radiological Sciences (NIRS) was established in 1957 as a special research institute for research and medical application of radiation, attached to the Science and Technology Agency of Japan. In 1961, NIRS started to use a Van de Graff accelerator (Model KN3000, High Voltage Engineering) for PIXE (Particle Induced X-ray Emission) analysis that was operated as a device for pre-tumor therapy with neutron and finally discarded in 1997. In March 1999, an electrostatic accelerator, HVEE Tandetron, was installed in the Electrostatic Accelerator Building for PIXE analysis. PIXE analysis is a trace analytical method, which has the advantage of simultaneous determination of elemental concentrations in a small specimen without any chemical separation by measuring characteristic X-rays of elements induced by accelerated charged nuclear particles such as protons. [1] In this paper, characteristics of the PIXE system and the new microbeam irradiation facility, Single Particle Irradiation System to Cell (SPICE), which is introduced to our Tandem accelerator are described., The 3rd International Symposium on Future Medical Engineering based on BIO-nanotechnology}, title = {Introduction of Micro-beam System in NIRS}, year = {2003} }