@misc{oai:repo.qst.go.jp:00060049,
 author = {Zhang, Hong and Yoshikawa, Kyosan and Tamura, Katsumi and Sago, Kenji and Zhang, Ming-Rong and Suhara, Tetsuya and Kamada, Tadashi and Tsuji, Hiroshi and Kandatsu, Susumu and Suzuki, Kazutoshi and Tanada, Shuji and Tsujii, Hirohiko and 張 宏 and 吉川 京燦 and 田村 克巳 and 佐合 賢治 and 張 明栄 and 須原 哲也 and 鎌田 正 and 辻 比呂志 and 神立 進 and 鈴木 和年 and 棚田 修二 and 辻井 博彦},
 month = {Oct},
 note = {To evaluate whether MET PET is valuable for imaging of osteosarcoma before and after carbon-ion radiotherapy (CIRT). 18 patients with osteosarcoma were performed with MET-PET before and after CIRT and analyzed visually and quantitatively. 16(88.9%) patients with osteosarcoma were clearly visible in the baseline MET PET study with a mean T/N ratio of 5.2+-2.9. The MET uptake decreased siginificantly to 2.6+-1.1 after CIRT(p<0.001). A siginificant reduction of tumor MET uptake of 39%+-27% was observed after CIRT. 16(88.9%) patients showed no local recurrence after CIRT with a median follow-up time of 20 months. Residual viable cells and necrosis of osteosarcoma were easily identified on MET PET image after CIRT. The results of this study showed that osteosarcoma could be effectively imaged with MET PET. MET PET might provide important metabolic information and help to distinguish residual viable cells and necrosis in osteosarcoma after CIRT. Thus this data permit the possible use for the therapeutic monitoring osteosarcoma treated by CIRT., 第43回　日本核医学会総会},
 title = {Imaging of Osteosarcoma with Positron Emission Tomography and 11C-Methionine},
 year = {2003}
}