{"created":"2023-05-15T14:43:25.228919+00:00","id":59475,"links":{},"metadata":{"_buckets":{"deposit":"f502a1aa-648c-4b7f-b046-49d73a2713e8"},"_deposit":{"created_by":1,"id":"59475","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"59475"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00059475","sets":["10:29"]},"author_link":["592009","592006","592008","592011","592007","592010"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2002-09-12","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The aim of this study was to compare lung tumour incidence measured in rats after inhalation exposure to aerosols containing alpha emitters which have different physico-chemical properties. Aerosols of radon and radon progeny, uranium ore dust, Np02, Pu02 or Cm203 were considered for inter-comparison with similar or different particle sizes. \n Dose-effect relationships for malignant lung tumour frequency appear linear up to a few Gy and then become infra linear at higher doses delivered to the lungs. The initial slope reflects the risk of lung tumour induction. The highest slopes of incidence were observed for radon and uranium ore dust (about 20%Gy-1) for which the most homogeneous alpha dose distribution to the lungs is expected. In a general trend, increasing the alpha activity of deposited particles (higher specific activity of constitutive radioisotopes or larger particle size) decreases the risk. The comparison of the reported data, shows that the risk per Gy at low doses (as well as DPUI) could vary over 1 order of magnitude depending on the physico-chemical properties of the aerosols. Mechanisms involved in the risk variation are discussed.","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"Workshop on Internal Doismetry of Radionuclides","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Fritsch, Paul"}],"nameIdentifiers":[{"nameIdentifier":"592006","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Dudoignon, Nicolas"}],"nameIdentifiers":[{"nameIdentifier":"592007","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Guillet, Kristel"}],"nameIdentifiers":[{"nameIdentifier":"592008","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Oghiso, Yoichi"}],"nameIdentifiers":[{"nameIdentifier":"592009","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Paul, Morlier Jean"}],"nameIdentifiers":[{"nameIdentifier":"592010","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"小木曽 洋一","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"592011","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"Does DPUI for inhaled actinide oxides actually reflect the risk of malignant lung tumor induction?","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Does DPUI for inhaled actinide oxides actually reflect the risk of malignant lung tumor induction?"}]},"item_type_id":"10005","owner":"1","path":["29"],"pubdate":{"attribute_name":"公開日","attribute_value":"2002-12-13"},"publish_date":"2002-12-13","publish_status":"0","recid":"59475","relation_version_is_last":true,"title":["Does DPUI for inhaled actinide oxides actually reflect the risk of malignant lung tumor induction?"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T22:04:31.037513+00:00"}