{"created":"2023-05-15T14:42:43.161845+00:00","id":58535,"links":{},"metadata":{"_buckets":{"deposit":"7cdbac7d-5b17-435c-bc91-088113ec2968"},"_deposit":{"created_by":1,"id":"58535","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"58535"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00058535","sets":["11"]},"author_link":["585276","585277"],"item_10004_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2015-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"205","bibliographicPageStart":"197","bibliographicVolumeNumber":"64","bibliographic_titles":[{"bibliographic_title":"RADIOISOTOPES"}]}]},"item_10004_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"陽電子放射断層撮像法(positron emission tomography: PET)と適切な放射性リガンドを用いるとヒトの脳内神経伝達物質の機能を可視化することができる。脳内には多くの神経伝達物質系が存在するが，コリン神経系は特に認知症の病態に深くかかわる神経系である。放射線医学総合研究所では脳内のアセチルコリンを分解するアセチルコリンエステラーゼの活性を測定する放射性リガンドを開発し，アルツハイマー病，レビー小体型認知症，パーキンソン病など多くの疾患の病態を明らかにしてきた。 ","subitem_description_type":"Abstract"}]},"item_10004_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"日本アイソトープ協会"}]},"item_10004_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0033-8303","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"篠遠, 仁"}],"nameIdentifiers":[{"nameIdentifier":"585276","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"篠遠 仁","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"585277","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"PETでみる認知症における神経伝達系の病態","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"PETでみる認知症における神経伝達系の病態"}]},"item_type_id":"10004","owner":"1","path":["11"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-04-20"},"publish_date":"2015-04-20","publish_status":"0","recid":"58535","relation_version_is_last":true,"title":["PETでみる認知症における神経伝達系の病態"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T22:14:56.962890+00:00"}