{"created":"2023-05-15T14:42:09.032951+00:00","id":57779,"links":{},"metadata":{"_buckets":{"deposit":"7b854214-8bc2-4396-bc93-ed9bcbb13c1e"},"_deposit":{"created_by":1,"id":"57779","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"57779"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00057779","sets":["11"]},"author_link":["581763","581765","581764","581766"],"item_10004_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2010-07","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"45","bibliographicPageStart":"40","bibliographicVolumeNumber":"9","bibliographic_titles":[{"bibliographic_title":"分子脳血管病 = Molecular Cerebrovascular Medicine"}]}]},"item_10004_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Positron emission tomography (PET)では投与する放射性リガンドの特性に基づいて、薬物の脳移行性（血液脳関門の透過性）を直接的または間接的に評価することが可能である。薬物の脳内の標的受容体での占有率を求めることにより、脳移行性を推定できる。また、血液脳関門に発現するP糖タンパクをはじめとするさまざまな薬物輸送トランスポーターのイメージングが可能になりつつある。","subitem_description_type":"Abstract"}]},"item_10004_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1346-8995","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"高野, 晴成"}],"nameIdentifiers":[{"nameIdentifier":"581763","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"須原, 哲也"}],"nameIdentifiers":[{"nameIdentifier":"581764","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"高野 晴成","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"581765","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"須原 哲也","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"581766","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"血液脳関門機能のイメージング -PETを用いた薬物の脳移行性の検討-","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"血液脳関門機能のイメージング -PETを用いた薬物の脳移行性の検討-"}]},"item_type_id":"10004","owner":"1","path":["11"],"pubdate":{"attribute_name":"公開日","attribute_value":"2010-10-01"},"publish_date":"2010-10-01","publish_status":"0","recid":"57779","relation_version_is_last":true,"title":["血液脳関門機能のイメージング -PETを用いた薬物の脳移行性の検討-"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T22:23:19.980400+00:00"}