{"created":"2023-05-15T14:42:01.353852+00:00","id":57606,"links":{},"metadata":{"_buckets":{"deposit":"7fc8913a-0e1d-438d-b9dc-ee9bca11b89c"},"_deposit":{"created_by":1,"id":"57606","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"57606"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00057606","sets":["11"]},"author_link":["580958","580947","580956","580940","580957","580945","580939","580943","580938","580941","580952","580942","580948","580946","580950","580937","580953","580955","580954","580949","580951","580944"],"item_10004_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2009-06","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"181","bibliographicPageStart":"171","bibliographicVolumeNumber":"44","bibliographic_titles":[{"bibliographic_title":"放射線生物研究"}]}]},"item_10004_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"高い線エネルギー付与が可能な炭素イオン線（以下、炭素線）照射は、癌臨床において、めざましい治療成績を挙げている。その基盤研究においても、炭素線の優れた抗腫瘍効果について、いくつかの研究成果が報告されている。一方、それらの研究は、in vitro 研究が主体で（1-5）、対象分子も限られたものが多い。マイクロアレイを用いた研究も散見されるが（表1）、その中で、私たちのグループでは、in vivo model 実験を基本に、炭素イオン線による腫瘍制御メカニズムの解明を目的に、分子生物学的研究を行っている(6,7)。本総説では、論文発表した基礎研究成果について解説し、更に、現在のマウスモデル研究の成果および子宮頸癌臨床サンプルを用いた基礎研究の検証実験結果を加えて報告する。","subitem_description_type":"Abstract"}]},"item_10004_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0441-747X","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"岩川, 眞由美"}],"nameIdentifiers":[{"nameIdentifier":"580937","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"野尻, 和典"}],"nameIdentifiers":[{"nameIdentifier":"580938","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"今留, 香織"}],"nameIdentifiers":[{"nameIdentifier":"580939","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"中渡, 美也子"}],"nameIdentifiers":[{"nameIdentifier":"580940","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"田巻, 倫明"}],"nameIdentifiers":[{"nameIdentifier":"580941","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"大野, 達也"}],"nameIdentifiers":[{"nameIdentifier":"580942","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"加藤, 真吾"}],"nameIdentifiers":[{"nameIdentifier":"580943","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"盛武, 敬"}],"nameIdentifiers":[{"nameIdentifier":"580944","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"中村, 悦子"}],"nameIdentifiers":[{"nameIdentifier":"580945","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"酒井, 美奈子"}],"nameIdentifiers":[{"nameIdentifier":"580946","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"今井, 高志"}],"nameIdentifiers":[{"nameIdentifier":"580947","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"岩川 眞由美","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"580948","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"野尻 和典","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"580949","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"今留 香織","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"580950","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"中渡 美也子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"580951","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"田巻 倫明","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"580952","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"大野 達也","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"580953","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"加藤 眞吾","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"580954","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"盛武 敬","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"580955","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"中村 悦子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"580956","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"酒井 美奈子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"580957","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"今井 高志","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"580958","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"重粒子線治療がもたらす生物学的効果−マウスモデルおよび子宮頸癌臨床材料を用いた解析−","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"重粒子線治療がもたらす生物学的効果−マウスモデルおよび子宮頸癌臨床材料を用いた解析−"}]},"item_type_id":"10004","owner":"1","path":["11"],"pubdate":{"attribute_name":"公開日","attribute_value":"2009-08-18"},"publish_date":"2009-08-18","publish_status":"0","recid":"57606","relation_version_is_last":true,"title":["重粒子線治療がもたらす生物学的効果−マウスモデルおよび子宮頸癌臨床材料を用いた解析−"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T22:25:15.638410+00:00"}