@article{oai:repo.qst.go.jp:00057419, author = {Matsumoto, Ryohei and Fukui, Kenji and Ushijima, Yo and Ito, Hiroshi and Suhara, Tetsuya and 松本 良平 and 須原 哲也}, issue = {4}, journal = {Progress in Neuro-Psychopharmacology & Biological Psychiatry}, month = {May}, note = {Previous functional neuroimaging studies have shown hyperactivity within cortico-subcortical circuits involving the orbitofrontal cortex (OFC), striatum, and thalamus in obsessive– compulsive disorder (OCD), and its normalization by treatment (Saxena and Rauch, 2000). On the other hand, symptoms of patients with OCD often shift within the symptom dimensions, waxing and waning during the clinical course (Mataix-Cols et al., 2002). Here we report regional cerebral blood flow (rCBF) changes using single photon emission computed tomography (SPECT) in the same patient through two relapse episodes of OC symptoms, in which the first and second OC symptoms shifted from one dimension to another.}, pages = {1082--1084}, title = {Recurrent Hyperperfusion in the Right Orbitofrontal Cortex in Obsessive-Compulsive Disorder}, volume = {32}, year = {2008} }